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The paper develops a SNP panel for identifying snow leopard individuals from fecal samples, validated with zoo and field samples, showing high accuracy and utility for population assessment.

The paper infers demographic and selective histories from population genomic data using a two-step approach, applied to human data to account for background selection effects.

This study investigates the effects of conditional dystrophin ablation in skeletal muscle and brain, revealing functional deficits and pathway dysregulation in both tissues.

The paper introduces a comprehensive equine allele-specific expression resource using integrated RNA sequencing and histone modification data from four Thoroughbreds across nine tissues.

This paper identifies systematic biases in malaria parasite relatedness estimation and proposes practical tools to address them.

This study shows that melanization limits polyploid cell growth during wound healing in Drosophila, ensuring efficient wound closure.

Pooling Fiber-seq gDNA with concatenated MAS-Seq cDNA in one PacBio run gives phased genome, methylome, chromatin, and transcriptome, exposing four gene disruptions from one X;13 translocation.

The paper identifies a novel SCN5A mutation, D372H, associated with Brugada syndrome and demonstrates its functional impact on sodium channel activity and expression.

This study investigates SAC function and biorientation pathways in Drosophila meiosis I, finding SAC is not required for chromosome segregation but some SAC proteins are involved in biorientation.

This study shows that gene expression and epigenetic states remain stable after CRISPR/Cas-mediated chromosomal inversions in Arabidopsis thaliana.

The paper estimates heritability of migration traits in mule deer using GPS and genomic data, finding low heritability for migration timing, distance, and duration but high heritability for movement rate.

The paper uses PCA to analyze biometric traits and indices of three indigenous sheep populations in Ethiopia, finding correlations with body weights and suggesting their suitability for different production purposes.

The paper introduces zTadCBE, a TadA-derived cytosine base editor for precise genome editing in zebrafish, showing high efficiency, reduced off-target effects, and expanded targeting range.

This paper identifies six key genes associated with vestibular migraine using bioinformatics analysis and suggests CABIN1 as a potential diagnostic biomarker.

RetroFun-RVS is a family-based rare-variant analysis method that integrates functional annotations to improve power and interpretability in complex disease studies.

This study shows that paternal chronic social instability stress reduces sperm miR-34c levels via astrocyte-derived exosomes, which are transmitted to offspring and contribute to transgenerational stress-related traits.

The paper identifies trimodal QTLs that jointly affect enhancer accessibility, promoter contacts, and gene expression in monocytes, revealing genetic links between enhancer activity and chromatin boundaries.

The paper introduces spatial-Mux-seq, a multi-modal spatial technology that profiles five modalities in tissues, revealing new insights into cell types, gene regulation, and epigenetic gradients in mouse embryos and brains.

The paper examines mis-splicing across human introns, tissues, and age using RNA-sequencing data, finding correlations with spliceosome components and age-related neurodegenerative disease genes.

The paper introduces dnaSORA, a diffusion transformer for DNA point clouds, achieving state-of-the-art classification of C. elegans data at 0.3 Mb resolution using synthetic data.