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This study observes specific patho-phenotypes in tomato leaves infiltrated with Ralstonia pseudosolanacearum, including petiole bending, epinasty, and senescence, which are hrp-dependent and not seen with other bacteria.

This study characterizes the genotypic and functional differences between healthy and pressure sore-derived fibroblasts, revealing reduced ECM protein expression and impaired myofibroblast differentiation.

The paper identifies BRRF1 as a key driver of transcriptome-wide splicing defects during gammaherpesvirus reactivation by hijacking the CCR4-NOT complex.

This study evaluates CT's accuracy in diagnosing equine TMJ osteoarthritis compared to histopathology, finding that specific CT features improve diagnostic accuracy.

The paper quantifies placental pathology and maternal perfusion in healthy primate pregnancies, revealing associations between stromal mineralization and reduced perfusion, and identifying key pathologies linked to vascular malperfusion.

DigitAb predicts cell types from H&E-stained slides using deep learning, achieving high accuracy without specialized assays or immunostains.

This study develops a dual-action nanoconjugate combining r-tPA and DNase to target r-tPA-resistant clots, showing improved reperfusion and reduced lesion volume in an ischemic stroke model.

This study investigates the role of ELMO1 in acute kidney injury, finding that ELMO1 deficiency increases tissue injury in cisplatin-induced AKI but not in ischemia-reperfusion models.

The paper investigates how hydraulic fracturing in aortic dissection causes medial damage beyond the false lumen, leading to structural weakening of the aortic wall.

This study develops a murine model of slow-progressing knee osteoarthritis by inducing non-invasive posterior cruciate ligament rupture and compares its progression to the destabilized medial meniscus model.

This paper introduces MorphoXAI, a human-in-the-loop framework for explaining AI predictions on whole-slide images, showing it provides accurate and interpretable histomorphological explanations at both global and local levels.

This study shows that Huntington disease in mice causes early embryonic changes in neocortical patterning, leading to postnatal sensorimotor deficits.

The paper compares collagen organization and crosslinking in IPF and NR-ARDS, finding differences in collagen maturity despite similar collagen content.

This study identifies ZFP384 as a regulator that impairs microglial reparative function after stroke, and shows that targeting ZFP384 enhances recovery even in the chronic phase.

The paper develops an AI-based method to generate spatial Banff t- and g-scores using spatial transcriptomics and histology, showing full concordance in severe rejection cases.

This study identifies hyperactivated glycolysis as a driver of spatially-patterned Kupffer cell depletion in MASLD, suggesting glucose metabolism as a therapeutic target.

This study investigates how 16p11.2 copy number variations affect genome architecture and transcription during neurodevelopment, finding both local dosage effects and broader chromatin changes.

This study examines VEGF isoform dynamics in COPD, finding altered VEGF-C and VEGF-A synthesis in fibroblasts and changes in VEGFR3 expression in lung tissue.

This study evaluates three long-acting ivermectin formulations in cattle to identify the most effective for malaria vector control, finding Mdc-STM-001 achieves sustained mosquitocidal efficacy for at least two months.

This study shows that CAVD patients have monocytes with pro-inflammatory and pro-calcific properties that promote valve disease progression.