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The paper quantifies age-related morphological changes in human skin using imageomics and shows xenografting induces rejuvenation-like changes regardless of host age.

This study shows that deleting the mitochondrial citrate carrier in kidney tubules reduces antibiotic-induced acute tubular injury by altering metabolism and increasing antioxidants.

This study overexpresses human SR-BI and BII in mice to examine their role in sepsis, finding increased mortality and organ damage linked to inflammation and phagocytosis.

The paper uses spatial transcriptomics and functional experiments to show SULF1 enhances VEGFR2 signaling and vascular remodeling in Moyamoya Disease.

This paper develops an automated framework for morphometric analysis of stented arterial cross-sections, achieving high accuracy and significantly reducing analysis time.

This study identifies structural defects in radicular and periodontal tissues in Hyp mice, linking them to refractory dental complications in X-linked hypophosphatemia.

The paper identifies iron deposition as a distinct phase of intraplaque hemorrhage, associated with inflammation and remodeling, through transcriptomic, histological, and metabolic analyses of human atherosclerotic plaques.

This study examines SKC mice to identify corneal phenotypes related to keratoconus, finding lower penetrance and male-specific abnormalities.

This study examines how bariatric surgery and metformin affect glucose regulation in diabetic rats, finding that their combination improves postprandial glucose control without enhancing insulin sensitivity or hormone secretion.

This study finds that Toxoplasma gondii exposure correlates with BPH in humans and induces prostatic hyperplasia and urinary dysfunction in mice.

This study shows that inhibiting CKAMP44 reduces seizure activity in TLE by increasing GluA1 phosphorylation and synaptic transmission through PPP3r2 regulation.

XpressO-Lung predicts spatial gene expression patterns in lung adenocarcinoma using histopathology images, validated against immunohistochemistry, showing strong concordance with known morphologic features.

This paper introduces a high-throughput histopathology workflow for complex in vitro models using 3D-printed histomolds, enabling efficient processing and analysis of multiple samples.

This paper develops a humanized anti-fibrotic antibody with a collagen-binding peptide to enhance targeting of fibrotic tissues and reduce post-traumatic scarring.

This study quantifies RRV titers in eriophyoid mites using qRT-PCR, revealing active replication in P. fructiphilus and no replication in P. adalius.

This study investigates how RANKL inhibition affects bone formation in a mouse model of fibrous dysplasia, finding that bone formation is restricted to specific surfaces rather than occurring diffusely.

This paper develops a method to quantify immunohistochemistry antigen concentrations and reaction-diffusion parameters, enabling more rigorous interpretation of IHC results.

The paper analyzes the topology of fibroblastic reticular cell networks in lymph nodes to predict breast cancer outcomes, finding that denser networks correlate with better or worse survival depending on disease stage and treatment.

The paper models IL-6 response in severe malaria using an ex vivo co-culture system and clinical data, showing that IL-6 is context-dependent and influenced by metabolic and thermal cues.

This study shows that PAD4-dependent NETosis and MPO contribute to inflammation, fibrosis, and arrhythmias in ACM, with targeting these pathways improving cardiac function.