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This study examines corticosterone release in seabird chicks under different feeding conditions and challenges, finding that their HPA response varies with environmental factors and external stimuli.

This study shows LOXL2 inhibition reduces pulmonary artery stiffness and improves survival in pulmonary hypertension models.

This study shows that human sPRR expressed in adipose tissue improves insulin sensitivity and endothelial function in obese female mice, but not in males.

The paper identifies c-fos expression in specific non-neuronal sites as an early indicator of spontaneous arousal from torpor in golden hamsters.

This paper shows that striatin (STRN) in cardiomyocytes is necessary for angiotensin II-induced cardiac hypertrophy and remodelling in mice, but not STRN3.

This study shows that targeting Snai1 in the right ventricle rescues pulmonary hypertension-induced failure by reducing EndMT, fibrosis, and FMT through a LOXL2-dependent mechanism.

This paper develops a framework to generate virtual retinal vasculatures and models their haemodynamics to study the relationship between vascular structure and retinal perfusion.

This study identifies N1-APA, a noncanonical polyamine produced by bacteria, as a bioactive metabolite that antagonizes animal mitochondrial function and macrophage activation.

This study uses snRNA-seq to analyze how exercise affects immune and mesenchymal cell interactions in epicardial adipose tissue of female pigs with coronary artery disease.

This study uses a TSC2 conditional knockout mouse model to show that mTORC1 activation in thyrocytes inhibits thyroid hormone biosynthesis, promotes growth, and leads to thyroid tumors.

The paper develops a cell culture insert model with hydrogels to study transplacental transport by incorporating stromal properties.

This study examines the effects of IFNT and PAG on endometrial and blood leukocyte transcriptomes in dairy cattle, identifying differentially expressed genes and their biological functions.

The paper uses a mathematical model to simulate weight loss trajectories under different interventions, finding that RYGB and GLP-1 agonists weaken appetite feedback and create larger persistent effects than calorie restriction.

This study measures auditory brainstem responses in Diversity Outbred mice to assess hearing variability across frequencies and sound levels.

This paper shows that GDF15 levels rise with psychosocial stress, depression, anxiety, and biological aging, and that saliva GDF15 has a distinct diurnal pattern and responds rapidly to acute stress.

The study identifies trabeculations in the human right ventricular outflow tract (RVOT) and shows they cause conduction delay and affect electrical propagation.

This study investigates the impact of proteolytic cleavage of the ENaC gamma subunit on Na+ and K+ handling in mice, finding that cleavage is not essential for channel activity in vivo.

The paper investigates copulatory wounding in alpacas during mating, finding that the penis reaches the uterine horns, causes abrasion, and may facilitate early pregnancy success through inflammatory responses.

This study combines pupillometry and drift-diffusion models to analyze auditory category learning dynamics, showing that delayed trials reveal distinct learning markers and DDM parameters.

This study integrates clinical and transcriptomic data to predict myocardial recovery in heart failure patients after LVAD implantation, identifying 80 features with an AUC of 0.731.