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This study evaluates the relative effects of diet correction and voluntary exercise on myocardial recovery in a murine HFpEF model, revealing sex-specific responses and residual anomalies in males.

This study shows that preterm growth-restricted lambs have altered cardiovascular responses to perinatal asphyxia, including impaired vascular contractility and dysregulated adrenergic receptor function.

This study shows that proliferation of early and mature osteoblasts is essential for bone fracture healing in mice, as blocking their proliferation leads to fibrous nonunion and reduced callus formation.

Handheld porometry, a 3D-printed leaf-clip microscope and YOLOv8 segmentation jointly phenotype stomatal conductance and anatomy on the same wheat leaf across 200 field genotypes.

This study identifies lactic acid from gut microbes as a key factor improving Drosophila survival during starvation by enhancing oxidative phosphorylation.

The paper identifies the SIRT1 IDR as a temporal gate for sequential TF recruitment during fasting, showing its role in metabolic adaptation.

This study shows NAT10 stabilizes progesterone receptor mRNA via ac4C modification, essential for uterine function and fertility in humans and mice.

This study examines how acute endurance exercise affects alternative splicing in skeletal muscle using short-read and long-read RNA sequencing, identifying significant changes in RNA-binding proteins and isoform expression.

This study investigates how pulsed transcranial photobiomodulation (tPBM) parameters affect EEG oscillations, finding parameter-dependent changes that contradict entrainment predictions and highlighting sex as a key biological modulator.

This study shows that platelets clear uropathogenic E. coli in a mouse model, leading to thrombocytopenia during sepsis.

The paper shows that saccades and fixations are coordinated with the cardiac cycle, with saccades occurring during systole and fixations during diastole.

The paper proposes a mechanism by which extracellular calcium regulates the resting state of outer-hair-cell bundles through changes in stereocilium height and builds a model to support this hypothesis.

This study shows that 12 weeks of voluntary wheel running restores glucagon sensitivity in middle-aged mice without affecting glucose homeostasis.

This paper presents a dataset of adult heart and liver mass in mice with placental IGF1 overexpression or insufficiency, showing sex-specific effects on heart mass.

The paper develops an in vitro system to mimic CoA-induced mechanical strain on endothelial cells and study NPRC dysfunction mechanisms.

This study shows that neuronal CaSR regulates energy and skeletal metabolism by modulating hypothalamic function in mice, affecting growth, bone mass, and metabolic parameters.

This study shows that cysteine restriction in mice causes rapid weight loss by depleting glutathione and coenzyme A, activating stress responses, and increasing lipolysis.

This study evaluates the effects of Tetradesmus obliquus Mi175.B1.a extract on gut function in vitro and in vivo, showing reduced permeability, restored tight junction proteins, and decreased inflammation.

This study investigates how disease-associated Kv1.3 variants affect protein folding and stability, finding that R114G variant shows reduced folding probability and structural instability.