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The paper evaluates antimicrobial peptide prediction tools and proposes a standardized evaluation framework to improve comparability and reproducibility.

The paper reports the structure of a peroxisomal import channel and shows how it adapts to transport proteins of different sizes.

The paper investigates the mechanism of peptide modifications by DybH and ChrH enzymes, identifying key steps in macrocyclization and heterocycle formation through mutational analysis.

This study identifies a conserved post-embryonic gene network in teleost fish that is responsive to thyroid hormone and ecological variation, showing how it evolves through gene copy number changes.

This study identifies naphthocyclinones as antibiotics produced by Streptomyces hederae in wild bee nests, mediating bacterial competition and showing potential against Paenibacillus larvae.

This study isolates two Hodarchaeales strains, closely related to the eukaryotic common ancestor, revealing their syntrophic, anaerobic, and oxygen-tolerant physiology and genomic features.

The paper examines phytoplankton beta diversity in Kenyan waterpans across seasons and land use, finding that genus replacement and weak spatial structure drive diversity patterns, with nutrient levels and cyanobacteria playing key roles in the dry season.

The paper identifies novel ciliary microtubule-associated proteins using BioID proximity labeling and proteomics, expanding the known repertoire of ciliary MAPs.

This study examines seasonal changes in cold and hypoxia tolerance in three winter-active pond insects, finding improved cold tolerance but no changes in hypoxia tolerance.

The paper identifies a novel neural code in the mouse medial frontal cortex that supports spatial generalization through extrapolation of coordinates across regions.

The paper shows that community performance curves predict temporal stability of ecological communities despite species interactions.

This study shows that adding hairpins to DNA tetrahedra increases their nuclease resistance, enhancing biostability through sequence-specific stabilization.

This study identifies T lymphocyte regulatory cytokines as predictors of frailty in older adults using machine learning and serum cytokine analysis.

The paper uses discrete-time quantum walks to predict critical residues in proteins involved in long-range interactions, validated experimentally on AsLOV2.

This study links the FREM3 gene to brain and cognitive aging using cross-species evidence from mice and humans, showing reduced brain volume and cognitive performance in Frem3 knockout mice and lower FREM3-GReX associated with reduced brain surface area and cognitive performance in humans.

This study examines dyadic coordination in a marmoset model of autism, finding heightened gaze responsiveness and unstable mutual gaze at close distances in affected pairs.

This study shows that BCAAs are sensed differently by mTOR and c-Myc in T cells, governing proliferation independently of catabolism.

The paper investigates D1/D2-SPN balance in FXS mice and shows that mGlu4 facilitation rescues social deficits.

The paper provides high-resolution HLA and MICA/MICB typing for the 1000 Genomes panel, identifying population-specific variants and demonstrating the utility of HLA data for predicting MIC genotypes.

This study uses BONCAT and conventional proteomics to identify infection-associated secreted proteins of Acinetobacter baumannii in A549 cells, revealing 152 proteins not detected in axenic cultures.