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The paper introduces DEEP-Boltz, a framework that extracts energetic potentials from protein structure predictors, outperforming existing methods in predicting mutation-induced stability changes.

This study examines how elevated CO2 affects photosynthesis and oxidative stress in two Caribbean coral species, finding increased O2 production but no significant changes in oxidative damage markers.

This paper develops a deep learning framework to localise the seizure onset zone from routine scalp EEG, achieving high accuracy and generalisation across datasets.

The paper identifies recurrent X-autosome fusions in Aeshna dragonflies, breaking 300 million years of karyotypic stasis and revealing patterns of neo-sex chromosome formation.

This paper characterizes OXA-57, a class D β-lactamase from Burkholderia pseudomallei, showing its activity against penicillins and cephalosporins, limited carbapenem hydrolysis, and structural insights into its mechanism.

This study shows that reduced mitochondrial fitness in CD8 T cells, caused by TFAM insufficiency, leads to increased immunopathology during viral pneumonia and impaired protective immunity.

The paper examines how low temperature and hypoxia, alone and together, affect recombination rates in Drosophila melanogaster across different genetic backgrounds.

The paper identifies small molecules that induce apoptosis in BRCA1-deficient cancer cells and links PPAR beta/delta inhibition to poor survival in breast cancer patients.

This study quantifies how viscosity, surface charge, and membrane interactions affect single-protein diffusion in GUVs, revealing membrane-proximal interactions and long-range charge effects.

The paper develops a dispersal model for Cenchrus setaceus in Mexican urban areas, predicting its spread and identifying containment strategies.

This study shows a single dose of a recombinant rVSV vaccine protects nonhuman primates from CCHFV infection, with immune responses similar to human survivors.

This paper develops an EEG-based graph model using frequency-resolved connectivity features to classify Alzheimer's and frontotemporal dementia against healthy controls, achieving competitive accuracy.

The paper investigates how membrane nanodomains influence constitutive activity of GPCRs, finding that A2AR is confined in nanodomains with Gas, promoting basal signaling.

The paper uses statistical analysis of mitochondrial genome data to identify convergent rearrangements in the WANCY region, suggesting it is a TDRL hotspot with higher convergence frequency than previously thought.

This study investigates the neuroprotective effects of Creatine Hydrochloride (C-HCl) on traumatic brain injury (TBI) in mice, finding sex-dependent benefits in reducing neuroinflammation, neurodegeneration, and inhibitory synaptic remodeling.

This study elucidates the mechanism of gelsolin activation through a combination of experimental and computational methods, revealing a dynamic, domain-dependent process leading to a heterogeneous active-state ensemble.

This study shows wild agoutis assess food preservability through oro-manual behavior, preferring to cache nuts over fresh fruits based on sensory information.

The paper maps the genome packaging landscape of AAV2 capsid protein using high-throughput synthesis and machine learning, revealing navigable subspaces of functionally viable sequences.

This study develops a regionally specific obesogenic diet for mice and shows it induces fat accumulation and metabolic issues in males but not females.

LynchRisk estimates Lynch syndrome probability using pedigree, cancer history, and tumor MMR status through a Bayesian model.