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This study investigates cellularization in Sphaeroforma arctica, showing microtubules help guide plasma membrane furrows to ensure equal partitioning of nuclei and cytoplasm during division.

This study identifies two distinct core minor pilin complexes in cyanobacteria that prime specialized Type IV filaments for natural competence and motility.

The paper investigates neurocognitive differences in perceptual feedback processing between autistic and non-autistic adults, finding reduced feedback-related negativity and weaker modulation by perceptual difficulty in autistic individuals.

The paper creates a comprehensive reference map of the RAS/RAF/MEK/ERK pathway interactomes and their mutation-driven rewiring, revealing new interactions and disease links.

This study identifies DBT and CK2 kinases as critical for temperature compensation in Drosophila circadian clocks through distinct phosphorylation pathways.

This study challenges assumptions about probiotic efficacy by showing heat-treated strains can match live strains in immunological activity at higher doses, using flow cytometry and machine learning to classify probiotic strains.

This study presents the first comprehensive phylogenomic analysis of Cypriniformes, establishing a robust backbone topology and identifying unresolved conflicts in evolutionary relationships.

This study shows UV radiation increases ribosome levels and translation capacity in filamentous fungi after filament formation, enhancing UV survival and repair through mechanisms involving TOR signaling and gene expression modules.

The paper develops a computational model to explain action selection in cluttered environments by integrating goal pursuit and obstacle avoidance through a weighted combination of control policies.

This paper reviews the impacts of El Nino-driven drought, fire, and smoke on non-human primates in Southeast Asia, finding habitat loss and smoke exposure affect primate behavior and health, with some recovery observed after forest regeneration.

This study uses molecular dynamics simulations to investigate how extracellular acidification affects the structure and function of HCN2 channels by disrupting hydrogen bond networks involving residue E212.

This paper introduces a method for continuous mass photometry of single molecules, enabling long-term observation of biomolecular interactions with high mass precision and temporal resolution.

This study identifies PDS5A as a key regulator of chromatin loop extrusion and TAD-like domains in Arabidopsis, revealing a promoter- and motif-based mechanism for loop anchoring and transcriptional control.

The paper develops a 3D computational model of mouse ventricular myocytes to show that calsequestrin2 (CASQ2) co-localization with RyR2 clusters is essential for reliable calcium wave propagation.

The paper isolates and cultures bacteria from four Mediterranean corals, identifying 84 pure isolates, including novel species, to better understand their roles in the coral holobiont.

HEPLISAV-B vaccine breaks HBV immune tolerance in a mouse model, inducing HBsAg clearance and anti-HBs immunity through CD4 T cell-dependent mechanisms.

The paper quantifies the fitness gain of DGR diversification compared to standard mutagenesis and identifies when DGR activation is evolutionarily favored.

This study shows that intermittent heat exposure during mid-to-late gestation in mice leads to reduced anogenital distance and increased hypospadias in male embryos, without affecting gene expression in the fetal testis.

This study examines how different inhibitors affect the dimerization of SARS-CoV-2 main protease, revealing distinct mechanisms of action between peptidomimetics and ebselen.

This paper shows that Porphyromonas gingivalis gingipain products induce CCL20 signaling and γδ T-cell accumulation in COPD-like airways via PAR-2 activation.