Author

G. H. Jang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. Notta· 3 shared S. Gallinger· 2 shared A. Devisme· 1 shared A. Dvorkin-Gheva· 1 shared A. Macklin· 1 shared A. Malik· 1 shared A. Sendoel· 1 shared B. G. Wouters· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

F. Notta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vivo CRISPR screens reveal SCAF1 and USP15 as novel drivers of pancreatic cancer

S. Martinez, R. Weber, T. Woo, A. Malik, M. Geuenich, G. H. Jang, D. Dervovic, K. Al-Zahrani, R. Tsai, N. Fodil, P. Gros, S. S. Sidhu, S. Gallinger, G. Neely, K. Campbell, , D. Schramek

This study uses in vivo CRISPR screens to identify USP15 and SCAF1 as novel tumor suppressors in pancreatic cancer, with potential therapeutic implications.

bioRxiv · Mar 13, 2022Cancer Biology

Spatially confined sub-tumor microenvironments orchestrate pancreatic cancer pathobiology

B. T. Grünwald, A. Devisme, G. Andrieux, F. Vyas, K. Aliar, C. W. McCloskey, A. Macklin, G. H. Jang, R. Denroche, J. M. Romero, P. Bavi, P. Bronsert, F. Notta, G. O'Kane, J. Wilson, , R. Khokha

This study identifies spatially confined sub-tumor microenvironments in PDAC that drive distinct tumor progression outcomes.

bioRxiv · Feb 18, 2021Cancer Biology

NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

P. Jain, A. Dvorkin-Gheva, E. Mollen, M. Xie, F. Jessa, P. Dhavarasa, S. Chung, K. R. Brown, G. H. Jang, F. Notta, J. Moffat, D. Hedley, P. C. Boutros, B. G. Wouters, M. Koritzinsky

This study identifies NOX4 as a link between metabolic deregulation and ER-specific redox vulnerability in PDAC, suggesting PRDX4 as a therapeutic target for pancreatic cancer.

bioRxiv · Oct 8, 2020Cancer Biology