Author

B. Michalke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. F. dos Santos· 1 shared A. Florez· 1 shared A. Katsarou· 1 shared A. Przybylla· 1 shared A. Rabinovich· 1 shared A. Schulze· 1 shared A. Trumpp· 1 shared A. Velentza· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. F. dos Santos

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Sodium chloride in the tumor microenvironment enhances T-cell metabolic fitness and cytotoxicity

D. Soll, M. Arunkumar, M. Alissa-Alkhalaf, S. Sun, T. Nguyen, C.-F. Chu, V. Lutz, S. Schauble, I. Garcia-Ribelles, M. Mueller, B. Michalke, G. Panagiotou, P. Schatzlmaier, H. Stockinger, W. Schamel, , C. E. Zielinski

This study shows sodium chloride enhances CD8+ T-cell metabolic fitness and cytotoxicity, improving tumor cell killing in vitro and in vivo.

bioRxiv · Sep 14, 2023Immunology

Selenocysteine metabolism is a targetable vulnerability in MYCN-amplified cancers

H. Alborzy, Z. Chen, U. Yildiz, F. Porto- Freitas, F. C. E. Vogel, J. Varga, J. Batani, C. Bartenhagen, W. Schmitz, G. Buechel, B. Michalke, J. Zheng, S. Meierjohann, E. Girardi, E. Espinet, , J. P. Friedmann Angeli

This study identifies LRP8 as a targetable vulnerability in MYCN-amplified neuroblastoma by showing its role in selenocysteine import and resistance to ferroptosis.

bioRxiv · May 17, 2022 · PreprintCancer Biology

A crosstalk between hepcidin and IRE/IRP pathways controls ferroportinexpression and determines serum iron levels in mice

E. Charlebois, C. Fillebeen, A. Katsarou, A. Rabinovich, K. Wisniewski, V. Venkataramani, B. Michalke, A. Velentza, K. Pantopulos

This study shows that hepcidin and IRE/IRP pathways interact to regulate ferroportin expression and serum iron levels in mice, with iron affecting hepcidin's ability to induce hypoferremia.

bioRxiv · Oct 29, 2021Immunology