A. I. d'Aquino

This paper develops a hydrogel-based GLP-1 receptor agonist delivery system that provides sustained therapy for up to 42 days in rats, improving diabetes management compared to daily injections.

This study develops polyacrylamide-based hydrogel coatings that improve the biocompatibility of implanted medical devices, extending their functional lifetime in animal models.

This paper introduces an amphiphilic copolymer excipient that enhances the stability of high-concentration monoclonal antibody formulations without affecting pharmacokinetics or injectability.

This paper develops an injectable hydrogel to co-deliver CAR-T cells and cytokines, enhancing solid tumor treatment in mice by creating a transient inflammatory niche.

This study shows that slow release of an RBD subunit vaccine via hydrogel enhances neutralizing antibody responses against SARS-CoV-2 compared to bolus administration.

This study develops an ultra-fast insulin-pramlintide co-formulation that improves glucose management in diabetic rats by mimicking endogenous co-secretion and reducing patient burden.