Author

L. Labanieh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

C. L. Mackall· 3 shared P. Xu· 3 shared A. Leruste· 2 shared D. D. Klysz· 2 shared E. Sotillo· 2 shared J. Huang· 2 shared J. R. Cochran· 2 shared K. A. Freitas· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersBioengineering

C. L. Mackall

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Engineered CD47 protects T cells for enhanced antitumor immunity

S. A. Yamada-Hunter, J. Theruvath, B. J. McIntosh, K. A. Freitas, M. T. Radosevich, A. Leruste, S. Dhingra, N. Martinez-Velez, P. Xu, A. Delaidelli, M. H. Desai, Z. Good, L. Labanieh, C. W. Mount, Y. Chen, , C. L. Mackall

This paper engineers a CD47 variant to protect T cells from macrophage clearance, enhancing antitumor efficacy by combining T cell and macrophage activation.

bioRxiv · Jun 20, 2023 · PreprintBioengineering

Inosine Induces Stemness Features in CAR T cells and Enhances Potency

D. D. Klysz, C. Fowler, M. Malipatlolla, L. Stuani, K. A. Freitas, S. Meier, B. Daniel, K. Sandor, P. Xu, J. Huang, L. Labanieh, A. Leruste, M. Bashti, V. Keerthi, J. Mata-Alcazar, , C. L. Mackall

This study shows that inosine enhances CAR T cell stemness and function by modulating metabolism and epigenetics, leading to improved anti-tumor potency.

bioRxiv · Apr 21, 2023Immunology

Delivery of CAR-T Cells in a Transient Injectable Stimulatory Hydrogel Niche Improves Treatment of Solid Tumors

A. K. Grosskopf, L. Labanieh, D. D. Klysz, G. Roth, P. Xu, O. Adebowale, E. C. G. C. Gale, C. K. Jons, J. H. Klich, J. Yan, C. L. Maikawa, S. Correa, B. S. Ou, A. I. d'Aquino, J. R. Cochran, , E. Appel

This paper develops an injectable hydrogel to co-deliver CAR-T cells and cytokines, enhancing solid tumor treatment in mice by creating a transient inflammatory niche.

bioRxiv · Dec 20, 2021Bioengineering

Live imaging of Aiptasia larvae, a model system for studying coral bleaching, using a simple microfluidic device

W. Van Treuren, K. Brower, L. Labanieh, D. Hunt, S. Lensch, B. Cruz, H. N. Cartwright, C. Tran, P. M. Fordyce

This paper introduces a microfluidic device to image live Aiptasia larvae and their algal symbionts under environmental stress, observing algal expulsion as a potential mechanism of coral bleaching.

bioRxiv · Jul 19, 2018Ecology