Author

A. J. Wood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Conway Morris· 1 shared A. Ewing· 1 shared A. Ferrer-Vacquer· 1 shared A. I. Isiaku· 1 shared A. J. Simpson· 1 shared A. Krishna· 1 shared A. M. Vassallo· 1 shared A. Meynert· 1 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperImmunology

A. Conway Morris

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signalling and clinical traits

A. Krishna, A. Meynert, M. Kelder, A. Ewing, S. Sheraz, A. Ferrer-Vacquer, G. Grimes, H. Becher, R. Silk, C. A. Semple, T. Kendall, A.-K. Hadjantonakis, T. Bird, J. A. Marsh, P. Hohenstein, , D. D. Ozdemir

The paper quantifies signalling effects of CTNNB1 mutations across cancer types and finds weakly activating mutations correlate with worse prognosis in hepatocellular carcinoma.

bioRxiv · Nov 9, 2023 · PreprintCancer Biology

The effects of antibiotic combination treatments on Pseudomonas aeruginosa tolerance evolution and coexistence with Stenotrophomonas maltophilia

J. P. Law, A. J. Wood, V.-P. Friman

This study examines how antibiotic combinations affect Pseudomonas aeruginosa tolerance evolution and coexistence with Stenotrophomonas maltophilia in CF infections.

bioRxiv · Mar 25, 2022Microbiology

A commercial antibody to the human condensin II subunit NCAPH2 cross-reacts with a SWI/SNF complex component

E. E. Cutts, G. C. Taylor, M. Pardo, L. Yu, J. Wills, J. S. Choudhary, A. Vannini, A. J. Wood

The paper identifies cross-reactivity of a commercial NCAPH2 antibody with SWI/SNF complex components, affecting immunoprecipitation experiments.

bioRxiv · Nov 7, 2020Cell Biology

Developmental regulation of mitotic chromosome formation revealed by condensin reporter mice

G. C. A. Taylor, L. A. Macdonald, M. Bui, L. Scott, I. Christodoulou, J. C. Wills, D. Papadopoulos, A. J. Wood

The paper investigates developmental regulation of mitotic chromosome formation using condensin reporter mice but retracts findings due to experimental artifacts related to cell-type differences.

bioRxiv · Nov 4, 2020 · PreprintCell Biology

Macrophages provide a transient muscle stem cell niche via NAMPT secretion

D. Ratnayake, P. D. Nguyen, F. J. Rossello, V. C. Wimmer, A. I. Isiaku, L. A. Galvis, A. J. Wood, Z. Julier, T. Boudier, V. Oorschot, K. L. Rogers, M. M. Martino, C. Marcelle, G. J. Lieschke, J. Bakkers, P. D. Currie

The paper identifies macrophages as a transient niche for muscle stem cells through NAMPT secretion, which activates CCR5 on stem cells to drive muscle regeneration.

bioRxiv · Aug 24, 2020Cell Biology

Complement C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodelling.

A. J. Wood, A. M. Vassallo, M.-H. Ruchard-Sparagano, J. Scott, C. Zinnato, C. Gonzalez-Tejedo, K. Kishore, C. D'Santos, A. J. Simpson, D. Menon, C. Summers, E. R. Chilvers, K. Okkenhaug, A. Conway Morris

This study identifies C5a-induced phosphoproteomic changes in human neutrophils that impair phagosomal maturation and acidification, leading to reduced killing of Staphylococcus aureus.

bioRxiv · Jan 17, 2020Immunology

Simulating the evolutionary trajectories of metabolic pathways for insect symbionts in the Sodalis genus

R. J. Hall, S. Thorpe, G. H. Thomas, A. J. Wood

The paper uses metabolic modeling and evolutionary algorithms to simulate the evolutionary trajectories of Sodalis glossinidius after internalization, showing gene loss impacts on evolved populations.

bioRxiv · Oct 25, 2019Evolutionary Biology