A. Joshi

A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants

A vaccine-induced human monoclonal antibody neutralizes SARS-CoV-2 and variants, reducing lung inflammation and viral load in hamsters.

Evolution of lower levels of inter-locus sexual conflict in D. melanogaster populations under strong selection for rapid development.

This study shows that D. melanogaster populations selected for rapid development evolved smaller body size and reduced inter-locus sexual conflict, with body size reduction primarily affecting male manipulative ability.

Multiple Shoot Regeneration from Excised Embryonic Axis Explants of Jute, Corchorus capsularis cv. JRC321

This study develops an in vitro protocol for multiple shoot regeneration from excised embryonic axis explants of jute, showing successful shoot differentiation and rooting.

APPLICATION OF GOOD AGRICULTURAL PRACTICES (GAP) BY THE BANANA FARMERS OF CHITWAN, NEPAL

This study assesses banana farming practices in Chitwan, Nepal, comparing them to Good Agricultural Practices (GAP), revealing low adoption rates and recommending awareness programs.

Consumption of a high energy density diet triggers microbiota dysbiosis, hepatic lipidosis, and microglia activation in the nucleus of the solitary tract in rats.

LC/MS-QToF Profiling, Anti-Diabetic and Anti-Adipogenic potential of Divya MadhuKalp: A Novel Herbo-mineral Formulation

This study evaluates the anti-diabetic and anti-adipogenic effects of the herbo-mineral formulation Divya MadhuKalp using in vitro and in vivo models.

Godanti Bhasma (anhydrous CaSO4) induces massive cytoplasmic vacuolation and cell survival response through stimulation of LC3 Associated Phagocytosis (LAP)

Salt-free fractionation of complex isomeric mixtures of glycosaminoglycan oligosaccharides compatible with ESI-MS and microarray analysis

This paper introduces a multi-dimensional separation method for glycosaminoglycan oligosaccharides that enables structural and functional analysis without desalting.

The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in maintaining mitochondrial metabolic homeostasis

This study shows TRAP1 forms an OXPHOS-regulated tetramer and is essential for maintaining mitochondrial metabolic homeostasis by modulating OXPHOS and interacting with mitochondrial chaperones.

Does Long-Term Selection for Development Time Result in Canalization: A Test Using Drosophila melanogaster

This study tests if long-term directional selection for reduced development time in Drosophila melanogaster increases canalization of that trait, finding increased canalization for development time but not pre-adult survivorship.

The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity

This study shows that cancer cells are hypersensitive to Hsp90 inhibitors due to a shift in cellular quiescence and activity balance, which can be modulated by growth factors and proteostasis challenges.

Contribution of mobile elements to the uniqueness of human genome with more than 15,000 human-specific insertions

The paper identifies 15,463 human-specific mobile elements (HS-MEs) contributing to genome size increase and gene regulation, expanding prior knowledge by over 8,000 elements.

ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in early stage Gallbladder Cancer

This study identifies ERBB2 and KRAS mutations in early-stage gallbladder cancer and shows their impact on response to EGFR inhibitors.

Complex interaction of resource availability, life-history and demography determines the dynamics and stability of stage-structured populations

This study uses a stage-structured model to show how resource availability, life-history traits, and demography affect population stability and the effectiveness of pest control.

Effects of Social Organization, Trap Arrangement and Density, Sampling Scale, and Population Density on Bias in Population Size Estimation Using Some Common Mark-Recapture Estimators

This study evaluates how social organization and other factors affect bias in population size estimation using mark-recapture methods, finding that POPAN performs better than Robust Design models under certain conditions.

Niche construction in evolutionary theory: the construction of an academic niche?

The paper critiques claims that niche construction is a significant evolutionary process, arguing that these claims are largely untenable and represent academic niche construction.