Author

A. Dhabaria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

B. Ueberheide· 6 shared K. H. Darwin· 2 shared S. H. Becker· 2 shared A. Floristan· 1 shared A. Gudur· 1 shared A. Heguy· 1 shared A. Khodadadi-Jamayran· 1 shared A. Nixon· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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6 shared papersMicrobiology

B. Ueberheide

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Geranylgeranylated-SCFFBXO10 Regulates Selective Outer Mitochondrial Membrane Proteostasis and Function

S. A. Bhat, Z. Vasi, L. Jiang, S. Selvaraj, R. Ferguson, A. Gudur, H. Ismail, R. Adhikari, A. Dhabaria, B. Ueberheide, S. Kuchay

This study identifies how geranylgeranylation of FBXO10 enables its targeting to the outer mitochondrial membrane, where it regulates PGAM5 ubiquitination and mitochondrial function.

bioRxiv · Apr 16, 2024 · PreprintCell Biology

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer

C. A. Chang, J. Jen, S. Jiang, A. Sayad, A. S. Mer, K. R. Brown, A. Nixon, A. Dhabaria, K. H. Tang, D. Venet, C. Sotiriou, J. Deng, K.-k. Wong, S. Adams, P. Meyn, , B. G. Neel

This study identifies drug-tolerant persisters (DTPs) in HER2+ breast cancer and reveals their origins and vulnerabilities to TKI resistance.

bioRxiv · Aug 28, 2020Cancer Biology

Mycobacterium tuberculosis Rv0991c is a redox-regulated molecular chaperone

S. H. Becker, K. Ulrich, A. Dhabaria, B. Ueberheide, W. N. Beavers, E. P. Skaar, L. M. Iyer, L. Aravind, U. Jakob, K. H. Darwin

This paper identifies Rv0991c in M. tuberculosis as a redox-regulated molecular chaperone essential for virulence, functioning similarly to Hsp33 in E. coli.

bioRxiv · Mar 5, 2020Microbiology

A DNA-guided Argonaute Protein Functions in DNA Replication in Thermus thermophilus

S. M. Jolly, I. Gainetdinov, K. Jouravleva, H. Zhang, L. Strittmatter, G. M. Hendricks, A. Dhabaria, B. Ueberheide, P. Zamore

The DNA-guided Argonaute protein TtAgo in Thermus thermophilus aids in separating daughter chromosomes after DNA replication.

bioRxiv · Dec 9, 2019Microbiology

Melanoma-secreted Amyloid Beta Supresses Neuroinflammation and Promotes Brain Metastasis

K. Kleffman, G. Levinson, E. Wong, F. Galan-Echevarria, R. Von-Itter, I. Rose, L. Blumenberg, A. Floristan, J. Tranos, D. Argibay, J. Chen, A. Dhabaria, E. de Miera Sainz de Vega, R. Rogers, Y. Zaim-Wadghiri, , E. Hernando

This study identifies amyloid beta as a factor secreted by melanoma cells that suppresses neuroinflammation and promotes brain metastasis.

bioRxiv · Nov 26, 2019Cancer Biology

The Mycobacterium tuberculosis Pup-proteasome system regulates nitrate metabolism through an essential protein quality control system

S. H. Becker, J. B. Jastrab, A. Dhabaria, C. Chaton, J. Rush, K. V. Korotkov, B. Ueberheide, K. H. Darwin

This study shows that the M. tuberculosis proteasome system regulates nitrate metabolism by controlling chaperonin gene expression through proteasome-mediated degradation of HrcA.

bioRxiv · Nov 14, 2018Microbiology