Author

A. Kirabo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 4 Biophysics· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell type annotation· 5 Organism:mouse· 5 Organism:human· 3 Assay:imaging· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. Neikirk· 7 shared A. Hinton· 6 shared H. K. Beasley· 5 shared Z. Vue· 5 shared A. G. Marshall· 4 shared C. N. Wanjalla· 4 shared E. Garza-Lopez· 4 shared L. Vang· 4 shared

Activity by Year

2022-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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7 shared papersPhysiology

K. Neikirk

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Strategies for Inducing and Validating Zinc Deficiency and Zinc Repletion

T.-Y. Wenegieme, D. Elased, J. Rockwood, K. Hasrat, K. McMichael, A. Marshall, K. Neikirk, A. Kirabo, K. Elased, A. Hinton, C. R. Williams

This paper provides validated dietary strategies to modulate zinc homeostasis in mice and outlines methods to assess zinc status, enhancing reproducibility in disease-related studies.

bioRxiv · Feb 28, 2024Physiology

Proteolytic Cleavage of the ENaC gamma Subunit: Impact Upon Na+ and K+ Handling

E. C. Ray, A. Nickerson, S. Sheng, R. Carrisoza-Gaytan, T. Lam, A. Marciszyn, L. Zhang, A. Jordahl, C. Bi, A. Winfrey, Z. Kou, S. Gingras, A. Kirabo, L. M. Satlin, T. R. Kleyman

This study investigates the impact of proteolytic cleavage of the ENaC gamma subunit on Na+ and K+ handling in mice, finding that cleavage is not essential for channel activity in vivo.

bioRxiv · Feb 12, 2024 · PreprintPhysiology

Human Heart Failure Alters Mitochondria and Fiber 3D Structure Triggering Metabolic Shifts

Z. Vue, P. T. Ajayi, K. Neikirk, A. Murphy, P. Prasad, B. C. Jenkins, L. Vang, E. Garza-Lopez, M. Mungai, A. G. Marshall, H. K. Beasley, M. Killion, R. Parker, J. Anukodem, K. Lavine, , A. Hinton

This study identifies structural and metabolic changes in human heart failure using SBF-SEM and metabolomic analyses.

bioRxiv · Nov 28, 2023 · PreprintPhysiology

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights into MFN-2 Mediated Changes

E. Scudese, Z. Vue, P. Katti, A. Marshall, M. Demirci, L. Vang, E. Garza Lopez, K. Neikirk, H. Le, D. Stephens, D. D. Hall, R. Rostami, T. Rodman, K. Kabugi, J.-q. Shao, , A. Hinton

This study investigates age-related changes in mitochondrial 3D structure in human skeletal muscle and shows that exercise can restore mitochondrial integrity through mitofusin 2.

bioRxiv · Nov 13, 2023Biophysics

Methods to Utilize Pulse Wave Velocity to Measure Alterations in Cerebral and Cardiovascular Parameters

A. G. Marshall, K. Neikirk, B. Shao, A. Crabtree, Z. Vue, H. K. Beasley, E. Garza-Lopez, E. Scudese, C. N. Wanjalla, A. Kirabo, C. Albritton, S. Jamison, M. Demirci, S. Murray, A. Cooper, , A. K. Reddy

This paper presents methods to measure impedance-based pulse wave velocity in systemic and cerebral vascular systems to study cardiovascular and cerebral parameters in Alzheimer's disease models.

bioRxiv · Jun 22, 2023Physiology

CD3+ T-cell: CD14+monocyte complexes are dynamic and increased with HIV and glucose intolerance

L. M. Obare, J. Simmons, J. Oakes, X. Zhang, C. Nochowivz, S. Priest, S. S. Bailin, C. M. Watten, M. Mashayekhi, H. K. Beasley, J. Shao, L. M. Meenderink, Q. Sheng, J. Stolze, R. Gangula, , C. N. Wanjalla

The paper identifies increased CD3+ T-cell:CD14+ monocyte complexes in diabetes and HIV, associated with inflammation and metabolic changes.

bioRxiv · Apr 24, 2023Immunology

Three-Dimensional Mitochondria Reconstructions of Murine Cardiac Muscle Changes in Size Across Aging

Z. Vue, K. Neikirk, L. Vang, E. Garza-Lopez, T. A. Christensen, J.-q. Shao, J. Lam, H. K. Beasley, A. G. Marshall, A. Crabtree, J. Anudokem, B. Rodriguez, B. Kirk, S. Bacevac, T. Barongan, , A. Hinton

This study uses 3D imaging to show that mitochondria in aging mouse hearts lose cristae structure and volume, similar to mutations in MICOS complex genes.

bioRxiv · Apr 23, 2022Biophysics

3D Reconstruction of Murine Mitochondria Exhibits Changes in Structure Across Aging Linked to the MICOS Complex

Z. Vue, E. Garza-Lopez, K. Neikirk, P. Katti, L. Vang, H. K. Beasley, J.-q. Shao, A. G. Marshall, A. Crabtree, A. C. Murphy, B. C. Jenkins, P. Prasad, C. S. Evans, B. T. Taylor, M. Mungai, , Murray

This study examines age-related changes in mitochondrial 3D structure in mouse muscle and heart tissues, linking these changes to the MICOS complex and metabolic alterations.

bioRxiv · Mar 22, 2022Biophysics