Author

B. Shao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 4 Organism:human· 3 Assay:electronic health records· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Crabtree· 5 shared A. Hinton· 5 shared E. Garza-Lopez· 5 shared K. Neikirk· 5 shared Z. Vue· 5 shared A. G. Marshall· 4 shared E. Scudese· 4 shared H. K. Beasley· 4 shared

Activity by Year

2022-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersBiophysics

A. Crabtree

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Quantitative Assessment of Morphological Changes in Lipid Droplets and Lipid-Mito Interactions with Aging in Brown Adipose

A. Crabtree, K. Neikirk, J. Pinette, A. Whiteside, B. Shao, J. McKenzie, Z. Vue, L. Vang, H. Le, M. Demirci, T. Ahmad, T. C. Owens, A. Oliver, F. Zeleke, H. K. Beasley, , A. Hinton

This study quantifies age-related changes in lipid droplet morphology and mitochondria-lipid interactions in murine brown adipose tissue using 3D imaging and analysis.

bioRxiv · Sep 23, 2023Biophysics

Methods to Utilize Pulse Wave Velocity to Measure Alterations in Cerebral and Cardiovascular Parameters

A. G. Marshall, K. Neikirk, B. Shao, A. Crabtree, Z. Vue, H. K. Beasley, E. Garza-Lopez, E. Scudese, C. N. Wanjalla, A. Kirabo, C. Albritton, S. Jamison, M. Demirci, S. Murray, A. Cooper, , A. K. Reddy

This paper presents methods to measure impedance-based pulse wave velocity in systemic and cerebral vascular systems to study cardiovascular and cerebral parameters in Alzheimer's disease models.

bioRxiv · Jun 22, 2023Physiology

Ablation of Sam50 is associated with fragmentation and alterations in metabolism in murine and human myotubes

B. Shao, M. Killion, A. Oliver, C. Vang, F. Zeleke, K. Neikirk, Z. Vue, E. Garza-Lopez, J.-q. Shao, M. Mungai, J. Lam, Q. Williams, C. Altamura, A. Whiteside, K. Kabugi, , A. Hinton

This study shows that Sam50 deficiency in myotubes leads to mitochondrial fragmentation, altered metabolism, and impaired oxidative capacity in both mice and humans.

bioRxiv · May 20, 2023Physiology

Defining Mitochondrial Cristae Morphology Changes Induced by Aging in Brown Adipose Tissue

A. Crabtree, K. Neikirk, A. Marshall, L. Vang, D. Stephens, B. Shao, E. Garza-Lopez, J. Lam, B. Rodriguez, M. Mungai, J. Stanley, D. Dean, J. Gaddy, E. Scudese, M. Sweetwyne, , A. Hinton

This study uses 3D electron microscopy to analyze mitochondrial cristae morphology in mouse brown adipose tissue across aging, finding significant structural changes in aged tissue.

bioRxiv · May 12, 2023Biophysics

JADE1 and HBO1/KAT7 proteins in the cytokinesis of epithelial cells. The role of PHD zinc fingers.

B. Shao, M. Panchenko

This study shows JADE1S delays cytokinesis by interacting with HBO1 and its PHD zinc fingers, while HBO1 promotes midbody dislocation of JADE1S.

bioRxiv · Oct 13, 2022 · PreprintCell Biology

Three-Dimensional Mitochondria Reconstructions of Murine Cardiac Muscle Changes in Size Across Aging

Z. Vue, K. Neikirk, L. Vang, E. Garza-Lopez, T. A. Christensen, J.-q. Shao, J. Lam, H. K. Beasley, A. G. Marshall, A. Crabtree, J. Anudokem, B. Rodriguez, B. Kirk, S. Bacevac, T. Barongan, , A. Hinton

This study uses 3D imaging to show that mitochondria in aging mouse hearts lose cristae structure and volume, similar to mutations in MICOS complex genes.

bioRxiv · Apr 23, 2022Biophysics

Structural and computational insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

x. wang, T. Wang, J. Ge, L. Zhang, J. Lan, X. He, Y. Ren, Z. Wang, H. Zhou, S. Fan, C. Zhu, D. Liu, B. Shao, T.-Y. Liu, Q. Wang

This study reports the crystal structure of the Omicron SARS-CoV-2 RBD-ACE2 complex and identifies key mutations enhancing ACE2 binding and immune escape.

bioRxiv · Jan 3, 2022 · PreprintBiophysics