A. R. Burns

Nemacol is a Small Molecule Inhibitor of C. elegans Vesicular Acetylcholine Transporter with Anthelmintic Potential

A small molecule screen identifies a vesicular acetylcholine transporter inhibitor scaffold that incapacitates parasitic nematodes.

Nementin is a Nematode-Selective Small Molecule Agonist of Neurotransmitter Release

A C. elegans-based screening pipeline identifies a selective nematicide that also potentiates acetylcholinesterase inhibitors.

Selective Control of Parasitic Nematodes Using Bioactivated Nematicides

This study identifies selectivins, a family of imidazothiazole nematicides that are selectively activated in nematodes, offering effective and selective control of plant-parasitic nematodes.

Microbiota Assembly, Structure, and Dynamics Among Tsimane Horticulturalists of the Bolivian Amazon

This study examines microbiota assembly in Tsimane infants and adults, finding that neutral processes dominate infant colonization, but are reduced in villages with more market access.

Gut feelings begin in childhood: how the gut metagenome links to early environment, caregiving, and behavior

The paper links gut microbiome composition to behavioral development in early school-aged children, showing associations with socioeconomic factors and specific taxa and functional modules.

A probabilistic model to identify the core microbial community

This paper introduces a probabilistic model to identify core microbial communities, revealing higher richness and diversity compared to conventional methods.

Different Munc18 Proteins Mediate Baseline and Stimulated Airway Mucin Secretion

The paper identifies distinct roles of Munc18 isoforms in baseline and stimulated airway mucin secretion, showing Munc18b's protective role in asthma and cystic fibrosis models.

Control of Mast Cell Regulated Exocytosis by Munc13 Proteins

This study identifies Munc13-4 as essential for mast cell regulated exocytosis and IgE-mediated anaphylaxis, while Munc13-2 plays a minor role.