Author

A. Machelart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

P. Brodin· 3 shared E. Hoffmann· 2 shared F. Trottein· 2 shared N. Deboosere· 2 shared V. Sencio· 2 shared A. Biela· 1 shared A. Danneels· 1 shared A. Mettouchi· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

P. Brodin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IRG1 controls host responses to restrict Mycobacterium tuberculosis infection

A. Machelart, I. Belhaouane, N. Deboosere, I. Poncin, J.-P. Saint-Andre, A.-M. Pauwels, O.-R. Song, S. Jouny, C. Rouanet, A. Poncet, S. Marion, W. Laine, J. Kluza, E. Muraille, R. Beyaert, , E. Hoffmann

This study shows that IRG1 controls host responses to restrict Mycobacterium tuberculosis infection by modulating immune cell function and limiting bacterial replication.

bioRxiv · May 4, 2022 · PreprintImmunology

A screening pipeline identifies a broad-spectrum inhibitor of bacterial AB toxins with cross protection against influenza A virus H1N1 and SARS-CoV-2

Y. Wu, N. Mahtal, L. Swistak, S. Sagadiev, M. Acharya, C. Demeret, S. Van der Werf, F. Guivel-Benhassine, O. Schwartz, S. Petracchini, A. Mettouchi, E. Paillares, L. Caramelle, P. Couvineau, R. Thai, , E. Lemichez

bioRxiv · Aug 13, 2021Microbiology

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice

S. Belouzard, A. Machelart, V. Sencio, T. Vausselin, E. Hoffmann, N. Deboosere, Y. Rouille, L. Desmarets, K. Seron, A. Danneels, C. Robil, L. Belloy, C. Moreau, C. Piveteau, A. Biela, , J. Dubuisson

This paper identifies clofoctol as an antiviral against SARS-CoV-2, showing it inhibits viral replication and reduces lung pathology in mice.

bioRxiv · Jun 30, 2021 · PreprintMicrobiology