A. Mund

Deep Visual Proteomics advances human colon organoid models by revealing a switch to an in vivo-like phenotype upon xenotransplantation

The paper uses Deep Visual Proteomics to show that human colon organoids switch to an in vivo-like phenotype after xenotransplantation.

A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics

This paper introduces a workflow for using membrane glass slides in histology and spatial proteomics, improving compatibility with automated staining and preserving antigen retrieval.

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

The paper identifies coronavirus-host protein interaction motifs, revealing SARS-CoV-2 specific mechanisms and a peptide-based inhibitor that blocks infection.

Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

The paper shows that gain-of-function mutations in FAM111A and FAM111B enhance protease activity, leading to DNA replication and transcription suppression and cell death, contributing to genetic disorders.

The fitness of Pseudomonas aeruginosa quorum sensing signal cheats is influenced by the diffusivity of the environment

The paper shows that QS signal molecules in Pseudomonas aeruginosa act as social public goods, with their accessibility influenced by environmental diffusivity and population structure.