Author

F. Mihalic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

L. Simonetti· 4 shared P. Jemth· 4 shared Y. Ivarsson· 4 shared A. Sayadi· 3 shared C. Benz· 3 shared E. Andersson· 3 shared J. Kliche· 3 shared M. Ali· 3 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBiochemistry

L. Simonetti

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The evolutionary and molecular history of a chikungunya virus outbreak lineage

J. Krambrich, F. Mihalic, M. W. Gaunt, J. Bohlin, J. Hesson, A. Lundkvist, X. de Lamballerie, C. Li, W. Shi, J. H.- O. Pettersson

This study traces the evolutionary origins and molecular changes of a chikungunya virus outbreak in Thailand, identifying mutations linked to increased virulence and transmission.

bioRxiv · Mar 15, 2024Microbiology

Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions

E. Kassa, S. Jamshidi, F. Mihalic, L. Simonetti, J. Kliche, P. Jemth, S. B. Lind, Y. Ivarsson

The paper evaluates biotinylated peptide pulldown and PRISMA coupled to mass spectrometry for capturing SLiM-based interactions, finding biotin-peptide pulldown more effective for validation.

bioRxiv · Oct 19, 2022Biochemistry

Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

F. Mihalic, L. Simonetti, G. Giudice, M. Rubin Sander, R. Lindqvist, M. B. A. Peters, C. Benz, E. Kassa, D. Badgujar, R. Inturi, M. Ali, I. Krystkowiak, A. Sayadi, E. Andersson, H. Aronsson, , Y. Ivarsson

The paper uses phage-based screening to identify 1,712 virus-host interactions mimicking host short linear motifs, revealing therapeutic targets for broad-spectrum antivirals.

bioRxiv · Jun 19, 2022 · PreprintBiochemistry

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

T. Kruse, C. Benz, D. H. Garvanska, R. Lindqvist, F. Mihalic, F. Coscia, R. Inturi, A. Sayadi, L. Simonetti, E. Nilsson, M. Ali, J. Kliche, A. Moliner Morro, A. Mund, E. Andersson, , Y. Ivarsson

The paper identifies coronavirus-host protein interaction motifs, revealing SARS-CoV-2 specific mechanisms and a peptide-based inhibitor that blocks infection.

bioRxiv · Apr 19, 2021Biochemistry

Proteome-scale amino-acid resolution footprinting of protein-binding sites in the intrinsically disordered regions of the human proteome

C. Benz, M. Ali, I. Krystkowiak, L. Simonetti, A. Sayadi, F. Mihalic, J. Kliche, E. Andersson, P. Jemth, N. E. Davey, Y. Ivarsson

The paper introduces HD2, a proteome-scale method for identifying and characterizing SLiM-mediated protein interactions with amino acid resolution, and provides tools for analyzing the results.

bioRxiv · Apr 13, 2021Biochemistry