Author

A. Sayadi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1

Frequent Co-Authors

C. Benz· 3 shared E. Andersson· 3 shared F. Mihalic· 3 shared L. Simonetti· 3 shared M. Ali· 3 shared N. E. Davey· 3 shared P. Jemth· 3 shared Y. Ivarsson· 3 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersBiochemistry

C. Benz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A possible genomic footprint of polygenic adaptation on population divergence in seed beetles?

G. Arnqvist, A. Sayadi

The paper investigates whether stabilizing selection on polygenic metabolic traits drives population divergence in seed beetles by analyzing genetic differentiation and functional enrichment.

bioRxiv · Sep 12, 2022Evolutionary Biology

Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

F. Mihalic, L. Simonetti, G. Giudice, M. Rubin Sander, R. Lindqvist, M. B. A. Peters, C. Benz, E. Kassa, D. Badgujar, R. Inturi, M. Ali, I. Krystkowiak, A. Sayadi, E. Andersson, H. Aronsson, , Y. Ivarsson

The paper uses phage-based screening to identify 1,712 virus-host interactions mimicking host short linear motifs, revealing therapeutic targets for broad-spectrum antivirals.

bioRxiv · Jun 19, 2022 · PreprintBiochemistry

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

T. Kruse, C. Benz, D. H. Garvanska, R. Lindqvist, F. Mihalic, F. Coscia, R. Inturi, A. Sayadi, L. Simonetti, E. Nilsson, M. Ali, J. Kliche, A. Moliner Morro, A. Mund, E. Andersson, , Y. Ivarsson

The paper identifies coronavirus-host protein interaction motifs, revealing SARS-CoV-2 specific mechanisms and a peptide-based inhibitor that blocks infection.

bioRxiv · Apr 19, 2021Biochemistry

Proteome-scale amino-acid resolution footprinting of protein-binding sites in the intrinsically disordered regions of the human proteome

C. Benz, M. Ali, I. Krystkowiak, L. Simonetti, A. Sayadi, F. Mihalic, J. Kliche, E. Andersson, P. Jemth, N. E. Davey, Y. Ivarsson

The paper introduces HD2, a proteome-scale method for identifying and characterizing SLiM-mediated protein interactions with amino acid resolution, and provides tools for analyzing the results.

bioRxiv · Apr 13, 2021Biochemistry

Sexual conflict drives micro- and macroevolution of sexual dimorphism in immunity

B. Bagchi, Q. Corbel, I. Khan, E. Payne, D. Banerji, J. Liljestrand-Ronn, I. Martinossi-Allibert, J. Baur, A. Sayadi, E. Immonen, G. Arnqvist, I. Soderhall, D. Berger

This study shows that sexual conflict influences sexual dimorphism in immunity through molecular and phenotypic changes in seed beetles.

bioRxiv · Dec 20, 2020Evolutionary Biology