Z. Qi

YAP promotes chromosomal instability by transcriptionally activating AJUBA through its super enhancer in breast cancer

This study identifies YAP's role in promoting chromosomal instability in breast cancer by activating AJUBA through its super enhancer, leading to AURKA activation and aberrant mitosis.

Deciphering the molecular mechanism underlying morphology transition in two-component DNA-protein cophase separation

The paper investigates DNA-protein co-condensates, identifying two morphology transitions and growth dynamics governed by DNA-p53 interaction strength.

Impact of Memory T Cells on SARS-COV-2 Vaccine Response in Hematopoietic Stem Cell Transplant

This study evaluates SARS-CoV-2 vaccine responses in HSCT recipients, finding memory T cell defects linked to reduced T cell responses despite humoral responses.

Ancient DNA in Lycoptera Fossils: Key Discoveries for Evolution and Methodological Reassessment

The paper extracts and analyzes ancient DNA from Lycoptera davidi fossils, identifies original DNA fragments, and introduces a new method for aDNA analysis and a novel genomic mechanism.

Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by sequential intermittent anti-PI3Ka/b/δ and anti-PD-1 treatment

This study shows that intermittent anti-PI3K treatment can overcome immune checkpoint therapy resistance in Pten-null prostate cancer by converting 'cold' tumors into T cell-inflamed ones.

Divergent cancer etiologies drive distinct B cell signatures and tertiary lymphoid structures

This study identifies distinct B cell signatures and tertiary lymphoid structures in HPV+ and HPV- HNSCC, highlighting their role in antitumor immunity.

Effects of carbon-based additive and ventilation rate on nitrogen loss and microbial community during chicken manure composting

The paper investigates how carbon-based additives and ventilation rates affect nitrogen loss and microbial communities in chicken manure composting, finding that woody peat reduces nitrogen loss more effectively than other additives.

SEMA3F-deficient colorectal cancer cells promote lymphangiogenesis: fatty acid metabolism replace glycolysis for energy supply during lymphatic endothelial cells proliferation in tumor hypoxia microenvironment

This study shows SEMA3F-deficient colorectal cancer cells enhance lymphangiogenesis under hypoxia by promoting fatty acid metabolism in lymphatic endothelial cells through IL-6 and PGC-1α-PPAR pathways.

A new strategy for selection of crop cultivated varieties based on yield factors driving and meteorological prediction

This paper proposes a strategy to select crop varieties based on yield factors and meteorological predictions, showing 70% and 50% success rates in two pilot regions for soybean variety selection.

Rice annexin OsANN4 interacting with OsCDPK24, reduces root aerenchyma formation by modulating H2O2 under ABA treatment

The paper identifies OsANN4 as a rice annexin that interacts with OsCDPK24, modulates H2O2 levels, and affects root aerenchyma formation under ABA treatment.