Author

D. Rajasundaram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

S. C. Watkins· 2 shared A. R. Cillo· 1 shared A. Sodhi· 1 shared A. Somasundaram· 1 shared A. Verma· 1 shared C. E. Hawes· 1 shared C. Lampenfeld· 1 shared C. T. Wallace· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

S. C. Watkins

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in atrophic AMD

S. Ghosh, R. Sharma, S. Bammidi, V. Koontz, M. Nemani, M. Yazdankhah, K. M. Kedziora, C. T. Wallace, C. Yu-Wei, J. Franks, D. Bose, D. Rajasundaram, S. Hose, J.-A. Sahel, R. Puertollano, , D. Sinha

This study identifies the AKT2/SIRT5/TFEB pathway as a therapeutic target for atrophic AMD by showing its role in lysosomal dysfunction and drusen formation in RPE cells.

bioRxiv · Aug 8, 2023 · PreprintCell Biology

Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C HIV-1 Vaccine in Rhesus Macaques

A. Verma, C. E. Hawes, S. R. Elizaldi, J. C. Smith, D. Rajasundaram, G. K. Pedersen, X. Shen, L. D. Williams, G. D. Tomaras, P. A. Kozlowski, R. R. Amara, S. S. Iyer

This study shows that inducing GC Tfh1 cells with MPLA+QS-21 adjuvant leads to higher and longer-lasting HIV-1 Env antibodies in rhesus macaques compared to CAF01.

bioRxiv · Jul 18, 2023 · PreprintImmunology

Systemic immune dysfunction in cancer patients driven by IL6 and IL8 induction of an inhibitory receptor module in peripheral CD8+ T cells

A. Somasundaram, A. R. Cillo, C. Lampenfeld, L. Oliveri, M. A. Velez, S. Joyce, M. J. Calderon, R. Dadey, D. Rajasundaram, D. P. Normolle, S. C. Watkins, J. G. Herman, J. M. Kirkwood, E. J. Lipson, R. L. Ferris, , D. A. A. Vignali

This study identifies a systemic immune dysfunction in cancer patients driven by IL6 and IL8, leading to CD8+ T cell dysfunction and poor prognosis.

bioRxiv · May 6, 2020 · PreprintCancer Biology