Author

A. Sivakumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

A. M. Harris· 2 shared F.-Y. Su· 2 shared G. A. Kwong· 2 shared H. Phuengkham· 2 shared A. H. Zamat· 1 shared C. A. Thiveaud· 1 shared C. R. Dixon· 1 shared C. Xu· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBioengineering

A. M. Harris

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Benzylic Trifluoromethyl Accelerates 1,6-Elimination Toward Rapid Probe Activation

L. Wang, A. Sivakumar, R. Zhang, S. Cho, Y. Kim, T. Aggarwal, L. Wang, E. C. Izgu

This paper introduces a fluorescent probe that rapidly detects hydrogen sulfide in live cells through a benzylic trifluoromethyl group-enhanced 1,6-elimination reaction.

bioRxiv · May 30, 2024 · PreprintBiochemistry

Sensitizing solid tumors to CAR-mediated cytotoxicity using synthetic antigens

L. Gamboa, A. H. Zamat, D. Vanover, C. A. Thiveaud, H. E. Peck, H. Phuengkham, A. Sivakumar, A. M. Harris, S. N. Dahotre, F.-Y. Su, P. J. Santangelo, G. A. Kwong

This study develops synthetic antigens to enhance CAR T cell efficacy against solid tumors by reducing off-target effects and improving tumor targeting.

bioRxiv · Dec 11, 2021 · PreprintBioengineering

Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy

R. Czapiewski, D. G. Batrakou, J. I. de las Heras, R. N. Carter, A. Sivakumar, M. Sliwinska, C. R. Dixon, S. Webb, G. Lattanzi, N. M. Morton, E. C. Schirmer

This study shows that Tmem120a knockout in mice disrupts fat genome organisation, leading to lipodystrophy and metabolic defects, with similarities to human FPLD2.

bioRxiv · Apr 12, 2021Cell Biology

Activity-based urinary biomarkers of response and resistance to checkpoint blockade immunotherapy

Q. D. Mac, C. Xu, J. R. Bowen, A. Sivakumar, H. Phuengkham, F.-Y. Su, S. Z. Stentz, H. Sim, A. M. Harris, T. T. Li, P. Qiu, G. A. Kwong

This paper develops INSIGHT, a mass-barcoded peptide sensor for noninvasive monitoring of checkpoint blockade therapy response and resistance in mice.

bioRxiv · Dec 10, 2020 · PreprintBioengineering