Author

Namit Chaudhary

Scripps Research InstituteORCID 0000-0002-2115-7731Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Darrell J. IrvineiD· 3 shared Agnes A. Walsh· 2 shared Akiko IwasakiiD· 1 shared Alexander Wang· 1 shared Ali A. AlbowaideyiD· 1 shared Amber M. Rauch· 1 shared Amir LedbetteriD· 1 shared Amrit Raj Ghosh· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersImmunology

Darrell J. IrvineORCID

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Author profile →

4 papers

Recent·Most cited

Atomic layer deposition for core-shell microparticle vaccines enabling programmable antigen delivery and enhanced humoral immune responses

Namit Chaudhary, Holly Coleman, Elias V. Paolone, Jiancheng Yu, Amir Ledbetter, Ashley A. Lemnios, Agnes A. Walsh, Heikyung Suh, Alexander Wang, Maryam M. Mansoor, JoLynn B. Giancola, Mariane B. Melo, Amber M. Rauch, Erika S. Langsfeld, Urvi R. Parlikar, , Darrell J. Irvine

This study develops ALD-coated microparticles for vaccines that enable controlled antigen release and enhance immune responses against HIV.

bioRxiv · Sep 2, 2026 · PreprintImmunology

Bioactive Enhanced Adjuvant Chemokine Oligonucleotide Nanoparticles (BEACON) for Mucosal Vaccination Against Genital Herpes

Sachin H. Bhagchandani, Stephen A. Ehrenzeller, Ivan Susin Pires, Namit Chaudhary, Carmen Jane Booth, Dong-il Kwon, Charalampia Koutsioumpa, Christopher A. Baker, Claire Laxton, Keyla Santos Guedes de Sá, Cullen Matthews, Priya Gill, Sarah Li, Anna Olszowka, Andrew Hudak, , Akiko Iwasaki

This paper develops BEACON, a mucosal adjuvant that enhances protective immunity against HSV-2 in mice by increasing CD8+ TRM populations and mucosal antibody responses.

Science Immunology · Jun 19, 2026Peer-reviewedImmunology

Rapid acquisition of HIV-1 neutralization breadth in a rhesus V2 apex germline antibody mouse model after a single bolus immunization

Amrit Raj Ghosh, Rumi Habib, Nitesh Mishra, Ryan S. Roark, Madhav Akauliya, Ali A. Albowaidey, Joel D. Allen, Khaled Amereh, Gabriel Avillion, Maria Bottermann, Bo Liang, Namit Chaudhary, Sean Callaghan, Jonathan Dye, Xuduo Li, , Facundo D. Batista

This study shows that a single immunization with a germline-targeting trimer can induce broad HIV-1 neutralizing antibodies in a rhesus macaque bnAb mouse model.

bioRxiv · Jun 12, 2025 · PreprintImmunology

Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines

Emily L. Meany, John H. Klich, Carolyn K. Jons, Tianyang Mao, Namit Chaudhary, Ashley Utz, Julie Baillet, Ye Eun Song, Olivia M. Saouaf, Ben S. Ou, Shoshana C. Williams, Noah Eckman, Darrell J. Irvine, Eric Andrew Appel

This paper improves mRNA vaccine efficacy by creating an inflammatory immune niche via injectable hydrogel depots that recruit immune cells and enhance humoral responses.

Science Advances · Apr 11, 2025Peer-reviewedBioengineering