Author

Andras Sziraki

Rockefeller University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 5

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:clustering· 2 Organism:human· 2

Frequent Co-Authors

Junyue CaoiD· 5 shared Jasper Lee· 4 shared Wei You ZhouiD· 4 shared Ziyu LuiD· 4 shared Abdulraouf AbdulraoufiD· 3 shared Zehao ZhangiD· 3 shared Andrew Shuh-Huei LiaoiD· 2 shared Chloe SchaeferiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenomics

Junyue CaoORCID

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5 papers

Recent·Most cited

EnrichSci: Transcript-guided Targeted Cell Enrichment for Scalable Single-Cell RNA Sequencing

Andrew Liao, Zehao Zhang, Andras Sziraki, Abdulraouf Abdulraouf, Zihan Xu, Ziyu Lu, Wei Hu Zhou, Junyue Cao

EnrichSci enables targeted profiling of specific cell types in complex tissues, revealing aging-associated molecular dynamics and post-transcriptional regulation.

bioRxiv · May 2, 2025 · PreprintGenomics

A Panoramic View of Cell Population Dynamics in Mammalian Aging

Zehao Zhang, Chloe Schaefer, Weirong Jiang, Ziyu Lu, Jasper Lee, Andras Sziraki, Abdulraouf Abdulraouf, Brittney D Wick, Maximilian Haeussler, Zhuoyan Li, Gesmira Molla, Rahul Satija, Wei You Zhou, Junyue Cao

PanSci, a single-cell transcriptome atlas of over 20 million cells throughout the mouse lifespan, unveils the temporal architecture of aging-associated cellular population dynamics, organ-specific immune cell shifts, and the lymphocytes role in organismal aging.

Science · Nov 28, 2024Peer-reviewedGenomics

A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in the human and mouse brains

Andras Sziraki, Ziyu Lu, Jasper Lee, Gábor Bányai, Sonya Anderson, Abdulraouf Abdulraouf, Eli Metzner, Andrew Shuh-Huei Liao, Jason R. Banfelder, Alexander E. Epstein, Chloe Schaefer, Zihan Xu, Zehao Zhang, Li Gan, Peter T. Nelson, , Junyue Cao

The paper develops a high-throughput single-cell genomics approach to study age-related and Alzheimer's disease-associated cell population dynamics and molecular signatures in human and mouse brains.

Nature Genetics · Nov 30, 2023Peer-reviewedGenomics

PerturbSci-Kinetics: Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens

Zihan Xu, Andras Sziraki, Jasper Lee, Wei You Zhou, Junyue Cao

PerturbSci-Kinetics enables analysis of transcriptome kinetics through single-cell RNA profiling of CRISPR screens, revealing key regulators in miRNA and mitochondrial RNA processing.

bioRxiv · Jan 29, 2023 · PreprintGenomics

A comprehensive view of cell-type-specific temporal dynamics in human and mouse brains

Ziyu Lu, Melissa Zhang, Jasper Lee, Andras Sziraki, Sonya Anderson, Shaoyu Ge, Peter T. Nelson, Wei You Zhou, Junyue Cao

This paper introduces TrackerSci, a technique to profile progenitor cells in mouse and human brains, revealing cell-type-specific dynamics and aging-related changes.

bioRxiv · Oct 1, 2022 · PreprintGenomics