Author
Zihan Xu
Rockefeller UniversityORCID 0009-0008-9317-9279Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
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2023-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 42 mutual co-author links6 papers
Recent·Most cited
- GenomicsNature CommunicationsPeer-reviewed
Single-cell multimodal profiling of pan-cancer cell lines uncovers gene regulatory principles underlying intrinsic cell states and environmental features
Zihan Xu, Aileen Ugurbil, Joshua Kwan…·Junyue Cao
This study constructs a pan-cancer single-cell multi-omic atlas to uncover gene regulatory principles in cancer cell states and environmental features across diverse cancer types.
- GenomicsSciencePeer-reviewed
Organism-wide cellular dynamics and epigenomic remodeling in mammalian aging
Ziyu Lu, Zehao Zhang, Zihan Xu…·Junyue Cao
This study constructs a single-cell chromatin accessibility atlas across mouse tissues to reveal age-related cellular and epigenomic changes, showing widespread population shifts and sex-dependent dynamics.
22 citationstop 1% - GenomicsbioRxivPreprint
Uncovering Convergent Cell State Dynamics Across Divergent Genetic Perturbations Through Single-Cell High-Content CRISPR Screening
Zihan Xu, Ziyu Lu, Aileen Ugurbil…·Junyue Cao
The paper introduces PerturbFate, a single-cell CRISPR screening platform, and finds convergent cell state dynamics across diverse genetic perturbations in melanoma cells.
1 citation - GenomicsbioRxivPreprint
Optics-free Spatial Genomics for Mapping Mouse Brain Aging
Abdulraouf Abdulraouf, Weirong Jiang, Zihan Xu…·Junyue Cao
IRISeq, an optics-free spatial transcriptomics method, uncovers aging-related changes in spatial gene expression and focal cell interactions in brain aging.
9 citations - GenomicsNature GeneticsPeer-reviewed
A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in the human and mouse brains
Andras Sziraki, Ziyu Lu, Jasper Lee…·Junyue Cao
The paper develops a high-throughput single-cell genomics approach to study age-related and Alzheimer's disease-associated cell population dynamics and molecular signatures in human and mouse brains.