Author

Anh Le

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aditi Sai Marella· 1 shared Allan I. LeveyiD· 1 shared Bismark Kojo AmohiD· 1 shared Carl Grant MangleburgiD· 1 shared David Gonzalez-MartineziD· 1 shared Hana BaderiD· 1 shared Ismael Al‐RamahiiD· 1 shared Jinghan ZhaoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperSystems Biology

Aditi Sai Marella

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2 papers

Recent·Most cited

EGFR suppression and drug-induced potentiation are widespread features of oncogenic RTK fusions

Yuzhi Gao, David Gonzalez-Martinez, Sofia Wissert, Hana Bader, Nidhi Sahni, Anh Le, Robert Charles Doebele, Lukasz J. Bugaj

The paper shows that RTK fusions suppress EGFR and sequester Grb2, and targeted therapies reverse this suppression, enhancing EGFR signaling and drug response.

bioRxiv · Nov 19, 2025 · PreprintCancer Biology

Systems genetic dissection of Alzheimer's disease brain gene expression networks

Pinghan Zhao, Omar El Fadel, Anh Le, Carl Grant Mangleburg, Justin S. Dhindsa, Timothy Wu, Jinghan Zhao, Meichen Huang, Bismark Kojo Amoh, Aditi Sai Marella, Yarong Li, Nicholas T. Seyfried, Allan I. Levey, Zhandong Liu, Ismael Al‐Ramahi, , Joshua M Shulman

This study uses a cross-species approach to identify gene expression networks linked to Alzheimer's disease pathology and neurodegeneration.

bioRxiv · Oct 4, 2024 · PreprintSystems Biology