Author

Robert Charles Doebele

University of Colorado AnschutzORCID 0000-0001-6728-6857Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Andriy MarusykiD· 1 shared Anh Le· 1 shared Bin FangiD· 1 shared Bina DesaiiD· 1 shared Daria MiroshnychenkoiD· 1 shared David Gonzalez-MartineziD· 1 shared Eric A. WelshiD· 1 shared Eric B. HauraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Andriy MarusykORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyScience SignalingPeer-reviewedDec 23, 2025

Cancer-associated fibroblasts confer ALK inhibitor resistance in EML4-ALK-driven lung cancer via concurrent integrin and MET signaling

Qianqian Hu, Lily L. Remsing Rix, Bina Desai…·Uwe Rix

This study identifies that CAFs confer ALK inhibitor resistance in EML4-ALK-driven lung cancer through both MET and integrin signaling pathways, and shows that targeting both pathways improves treatment efficacy.

6 citations

mouseproteomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 19, 2025

EGFR suppression and drug-induced potentiation are widespread features of oncogenic RTK fusions

Yuzhi Gao, David Gonzalez-Martinez, Sofia Wissert…·Lukasz J. Bugaj

The paper shows that RTK fusions suppress EGFR and sequester Grb2, and targeted therapies reverse this suppression, enhancing EGFR signaling and drug response.

3 citations

humanproteomics

𝕏 PostBluesky