Author

Anna Kurianowicz

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Julia RosecransiD· 2 shared Mélanie OttiD· 2 shared Taha Y. TahaiD· 2 shared Annette ChoiiD· 1 shared Brian ImbiakhaiD· 1 shared Cecilia Vagi-Szmola· 1 shared Charles S. CraikiD· 1 shared Chengjin YeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

Julia RosecransORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Coupling high-throughput protease enzymology with viral replication reveals biochemical constraints of viral fitness

Dylan Aidlen, William Vinh Thanh Vo, Nicholas J. Young, Julia Rosecrans, Anna Kurianowicz, Shih‐Wei Chuo, Garrison P. R. Asper, Dashiell Anderson, Jacob A. Posner, Duncan F. Muir, Nicholas Freitas, Mélanie Ott, Charles S. Craik, Taha Y. Taha, Margaux M. Pinney

The paper links protease sequence variation to biochemical parameters and viral fitness using high-throughput enzymology and replication assays.

bioRxiv · Jan 28, 2026 · PreprintBiochemistry

Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6

Taha Y. Taha, Shahrzad Ezzatpour, Jennifer M. Hayashi, Chengjin Ye, Francisco José Zapatero Belinchón, Julia Rosecrans, Gabriella R. Kimmerly, Irene P. Chen, Keith Walcott, Anna Kurianowicz, Danielle M. Jorgens, Natalie R. Chaplin, Annette Choi, David W. Buchholz, Julie Sahler, , Mélanie Ott

This study identifies the L260F mutation in NSP6 as enhancing RNA replication and pathogenesis in recent SARS-CoV-2 variants, independent of Spike function.

PLoS Pathogens · Mar 31, 2025Peer-reviewedMicrobiology