Author

Dashiell Anderson

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:virus· 1

Frequent Co-Authors

Charles S. CraikiD· 3 shared Julia RosecransiD· 2 shared Mélanie OttiD· 2 shared Taha Y. TahaiD· 2 shared Tyler C. DetomasiiD· 2 shared Aakriti JainiD· 1 shared Adam R. RensloiD· 1 shared Alicia RichardsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersBiochemistry

Charles S. CraikORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Coupling high-throughput protease enzymology with viral replication reveals biochemical constraints of viral fitness

Dylan Aidlen, William Vinh Thanh Vo, Nicholas J. Young, Julia Rosecrans, Anna Kurianowicz, Shih‐Wei Chuo, Garrison P. R. Asper, Dashiell Anderson, Jacob A. Posner, Duncan F. Muir, Nicholas Freitas, Mélanie Ott, Charles S. Craik, Taha Y. Taha, Margaux M. Pinney

The paper links protease sequence variation to biochemical parameters and viral fitness using high-throughput enzymology and replication assays.

bioRxiv · Jan 28, 2026 · PreprintBiochemistry

Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus-MPro inhibitors with potent in vivo efficacy

Tyler C. Detomasi, Gilles Degotte, Sijie Huang, Rahul K. Suryawanshi, Amy Diallo, Luca Lizzadro, Francisco José Zapatero Belinchón, Taha Y. Taha, Jiapeng Li, Alicia Richards, Eric R. Hantz, Zain Alam, Mauricio Montaño, Maria McCavitt-Malvido, Rajesh Gumpena, , Charles S. Craik

This paper describes the discovery of new coronavirus MPro inhibitors with improved pharmacokinetics, broad-spectrum antiviral activity, and superior in vivo efficacy compared to existing drugs.

Science Advances · Apr 23, 2025Peer-reviewedBiochemistry

Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Aakriti Jain, Isaac P. Heremans, Gilles Rademaker, Tyler C. Detomasi, Peter J. Rohweder, Dashiell Anderson, Justin Zhang, Grace A. Hernandez, Suprit Gupta, Teresa von Linde, Mike Lange, Martina Spacci, Jiayi Luo, Y. Rose Citron, James A. Olzmann, , Roberto Zoncu

The paper identifies LyLAP as a key enzyme for lysosomal degradation of transmembrane proteins, showing its role in maintaining endocytic activity and lysosomal stability in pancreatic cancer.

Science · Mar 27, 2025Peer-reviewedBiochemistry