Author

Gabriella R. Kimmerly

Gladstone InstitutesORCID 0000-0002-2920-2218Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexander MarsoniD· 1 shared Alexis TalbotiD· 1 shared Allison Grace RothrockiD· 1 shared Angela ToiD· 1 shared Anna Kurianowicz· 1 shared Annette ChoiiD· 1 shared Avishai ShemeshiD· 1 shared Brian ImbiakhaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Alexander MarsonORCID

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2 papers

Recent·Most cited

Site-specific genome engineering of primary human natural killer cells for programmable anti-tumor function

Vincent Allain, Allison Grace Rothrock, Pierre-Louis Bernard, William A. Nyberg, Alexis Talbot, Joseph J. Muldoon, Jing-Yi Chung, Angela To, Christopher R. Chang, Gabriella R. Kimmerly, Chang Liu, Tasha Tsao, Yasaman Mortazavi, Jin Seo, Zhongmei Li, , Justin Eyquem

This paper develops a genome engineering workflow for primary human NK cells using CRISPR/Cas9 and AAV6 to integrate and disrupt genes, enhancing anti-tumor function through targeted CAR expression.

bioRxiv · Oct 5, 2025 · PreprintImmunology

Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6

Taha Y. Taha, Shahrzad Ezzatpour, Jennifer M. Hayashi, Chengjin Ye, Francisco José Zapatero Belinchón, Julia Rosecrans, Gabriella R. Kimmerly, Irene P. Chen, Keith Walcott, Anna Kurianowicz, Danielle M. Jorgens, Natalie R. Chaplin, Annette Choi, David W. Buchholz, Julie Sahler, , Mélanie Ott

This study identifies the L260F mutation in NSP6 as enhancing RNA replication and pathogenesis in recent SARS-CoV-2 variants, independent of Spike function.

PLoS Pathogens · Mar 31, 2025Peer-reviewedMicrobiology