Author

T. W. Foreman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:rat· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Sette· 4 shared C. E. Nelson· 4 shared D. L. Barber· 4 shared K. D. Kauffman· 4 shared L. E. Via· 4 shared J. M. Brenchley· 3 shared N. E. Lora· 3 shared S. Sakai· 3 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

A. Sette

Mutual co-authors in cluster

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4 papers

Recent·Most cited

IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

C. E. Nelson, T. W. Foreman, K. D. Kauffman, S. Sakai, S. T. Gould, J. D. Fleegle, F. Gomez, NIAID/DIR Tuberculosis Imaging Program, C. Le Nouen, X. Liu, T. L. Burdette, N. L. Garza, B. A. P. Lafont, K. Brooks, C. S. L. Arlehamn, , D. L. Barber

This study examines the roles of IFNγ and IL-10 in SARS-CoV-2 infection of rhesus macaques, finding IL-10 suppresses T cell expansion but promotes tissue-resident memory cell formation.

bioRxiv · Sep 13, 2022Immunology

Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues

C. E. Nelson, S. Namasivayam, T. W. Foreman, K. D. Kauffman, S. Sakai, D. E. Dorosky, N. E. Lora, NIAID/DIR Tuberculosis Imaging Program, K. Brooks, E. L. Potter, M. Roederer, A. Sher, D. Weiskopf, A. Sette, E. de Wit, , D. L. Barber

This study shows that SARS-CoV-2 replication declines in the lungs before T cell responses, while innate immunity restricts viral replication in nasal and oral mucosa in rhesus macaques.

bioRxiv · Jan 6, 2022Immunology

CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection

T. W. Foreman, C. E. Nelson, K. D. Kauffman, N. E. Lora, C. L. Vinhaes, D. E. Dorosky, S. W. Sakai, F. Gomez, J. D. Fleegle, M. Parham, S. R. Perera, C. S. Lindestam Arlehamn, A. Sette, Tuberculosis Imaging Program, J. M. Brenchley, , D. L. Barber

This study shows that acute SIV co-infection rapidly depletes CD4 T cells from tuberculosis granulomas before systemic CD4 T cell loss or disease reactivation.

bioRxiv · Dec 17, 2021Immunology

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

K. D. Kauffman, S. Sakai, N. E. Lora, S. Namasivayam, P. J. Baker, O. Kamenyeva, T. W. Foreman, C. E. Nelson, D. Oliveira-de-Souza, C. L. Vinhaes, Z. Yaniv, C. S. Lindestam Arleham, A. Sette, G. J. Freeman, R. Moore, , D. L. Barber

This study shows that PD-1 blockade worsens Mycobacterium tuberculosis infection in rhesus macaques by increasing bacterial loads and altering immune responses.

bioRxiv · Aug 5, 2020Immunology