Author

Benjamin K. Law

Princeton University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Amit ChoudharyiD· 2 shared Michelle M. ChaniD· 2 shared Vedagopuram SreekanthiD· 2 shared Adriano BolondiiD· 1 shared Alexander J. StrzalkowskiiD· 1 shared Benjamin J. RaphaeliD· 1 shared Bridget K. WagneriD· 1 shared Celeste M. NelsoniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

Amit ChoudharyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mapping embryonic mouse lung development using enhanced spatial transcriptomics

Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan

This study uses spatial transcriptomics to map cell type organization during mouse lung development, identifying new mesenchymal clusters and dynamic changes in epithelial progenitors.

Advanced Science · Sep 27, 2026Peer-reviewedDevelopmental Biology

Inferring cell differentiation maps from lineage tracing data

Palash Sashittal, Richard Y. Zhang, Benjamin K. Law, Henri Schmidt, Alexander J. Strzalkowski, Adriano Bolondi, Michelle M. Chan, Benjamin J. Raphael

The paper introduces Carta, an algorithm that infers cell differentiation maps from single-cell lineage tracing data, showing improved accuracy over existing methods in simulated and real data.

Nature Methods · Dec 8, 2025Peer-reviewedBioinformatics

Orthogonal resistance mechanisms of classical- and induced-proximity inhibitors

Manuel L. Merz, Karishma Kailass, Rajaiah Pergu, Kien Tran, Kritika Gupta, Zachary C. Severance, Sameek Singh, Vedagopuram Sreekanth, Benjamin K. Law, Gideon Rosenblatt, Rohil Dhaliwal, Amit Choudhary

This study shows induced-proximity inhibitors have orthogonal resistance mechanisms to classical inhibitors, using KRAS as a model system.

bioRxiv · May 10, 2025 · PreprintBiochemistry

A conjugation platform for CRISPR-Cas9 allows efficient β-cell engineering

Donghyun Lim, Vedagopuram Sreekanth, Kurt J. Cox, Benjamin K. Law, Bridget K. Wagner, Jeffrey M. Karp, Amit Choudhary

This paper introduces a CRISPR-Cas9 conjugation platform for multivalent display of molecules, enhancing genome editing precision and enabling β-cell engineering to secrete interleukin-10.

Nature Communications · Aug 13, 2020Peer-reviewedSynthetic Biology