Author

Bin E. Li

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

Stuart H. OrkiniD· 2 shared Yuko FujiwaraiD· 2 shared Alejo Rodriguez-FraticelliiD· 1 shared Danni Hong· 1 shared Davide SeruggiaiD· 1 shared Duluxan SritharaniD· 1 shared Fernando D. CamargoiD· 1 shared Fernando G. OsorioiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Stuart H. OrkinORCID

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2 papers

Recent·Most cited

An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cells

Sarah Bowling, Duluxan Sritharan, Fernando G. Osorio, Maximilian Nguyen, Priscilla Cheung, Alejo Rodriguez-Fraticelli, Sachin H Patel, Wei-Chien Yuan, Yuko Fujiwara, Bin E. Li, Stuart H. Orkin, Sahand Hormoz, Fernando D. Camargo

The paper introduces a CRISPR/Cas9 mouse line (CARLIN) to simultaneously track lineage histories and gene expression in single cells, revealing clonal bottlenecks in hematopoietic stem cells.

Cell · May 14, 2020Peer-reviewedDevelopmental Biology

Enhancer-dependence of gene expression increases with developmental age

Wenqing Cai, Jialiang Huang, Qian Zhu, Bin E. Li, Davide Seruggia, Pingzhu Zhou, Minh Nguyen, Yuko Fujiwara, Huafeng Xie, Zhenggang Yang, Danni Hong, Pengfei Ren, Jian Xu, William T. Pu, Guo‐Cheng Yuan, Stuart H. Orkin

The paper shows that enhancer-dependence of gene expression increases with developmental age in mouse and human cells.

bioRxiv · Jun 21, 2019 · PreprintMolecular Biology