Author

C. A. Ruiz-Bedoya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

S. K. Jain· 3 shared K. Flavahan· 2 shared A. A. Ordonez· 1 shared A. Braxton· 1 shared A. Cimini· 1 shared A. Jedlicka· 1 shared A. Mueller· 1 shared A. Napiorkowski· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMicrobiology

S. K. Jain

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Author profile →

3 papers

Recent·Most cited

The SARS-CoV-2 spike protein binds and modulates estrogen receptors

O. Solis, A. R. Beccari, D. Iaconis, C. Talarico, C. A. Ruiz-Bedoya, J. C. Nwachukwu, A. Cimini, V. Castelli, R. Bertini, M. Montopoli, V. Cocetta, S. Borocci, I. G. Prandi, K. Flavahan, M. Bahr, , M. Michaelides

This study identifies a novel interaction between SARS-CoV-2 spike protein and estrogen receptor alpha, showing its role in modulating ER activity and ACE2 expression in infected cells and tissues.

bioRxiv · May 21, 2022Immunology

Adjunctive inhibition of the integrated stress response pathway accelerates bacterial clearance in a mouse model of tuberculosis

S. Krug, P. Prasad, S. Xiao, S. Lun, C. A. Ruiz-Bedoya, M. Klunk, A. A. Ordonez, S. K. Jain, G. Srikrishna, I. Kramnik, W. Bishai

This study shows that inhibiting the Integrated Stress Response (ISR) pathway alongside standard TB antibiotics reduces bacterial loads and accelerates sterilization in a mouse model of tuberculosis.

bioRxiv · Dec 31, 2021 · PreprintMicrobiology

Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model

S. Dhakal, C. A. Ruiz-Bedoya, R. Zhou, P. Creisher, J. Villano, K. Littlefield, J. Castillo, P. Marinho, A. Jedlicka, A. Ordonez, N. Majewska, M. Betenbaugh, K. Flavahan, A. Mueller, M. Looney, , S. L. Klein

This study shows that male golden Syrian hamsters experience more severe lung disease and lower antiviral antibody responses compared to females after SARS-CoV-2 infection.

bioRxiv · Apr 2, 2021Microbiology