Author

T. Konuma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Nishiyama· 2 shared K. Arita· 2 shared M. Nakanishi· 2 shared T. Ikegami· 2 shared Y. Chiba· 2 shared A. Nagadoi· 1 shared C. B. Mulholland· 1 shared C. Tsuchiya· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

A. Nishiyama

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3 papers

Recent·Most cited

Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3

N. Shiraishi, T. Konuma, Y. Chiba, S. Hokazono, N. Nakamura, M. H. Islam, M. Nakanishi, A. Nishiyama, K. Arita

This study compares the structural and functional differences between human and mouse DPPA3 in binding to UHRF1 PHD finger, showing weaker human DPPA3 binding and reduced inhibition of UHRF1 chromatin binding.

bioRxiv · Jan 11, 2024Biochemistry

NMR analysis of the homodimeric structure of a D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria

T. Konuma, T. Takai, C. Tsuchiya, M. Nishida, M. Hashiba, Y. Yamada, H. Shirai, A. Nagadoi, E. Chikaishi, K.-i. Akagi, S. Akashi, T. Yamazaki, H. Akutsu, T. Ikegami

The paper determines the dimeric structure of VanX using NMR and identifies a monomeric form for inhibitor screening.

bioRxiv · Oct 13, 2023Biochemistry

Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger

K. Hata, N. Kobayashi, K. Sugimura, W. Qin, D. Haxholli, Y. Chiba, S. Yoshimi, G. Hayashi, H. Onoda, T. Ikegami, C. B. Mulholland, A. Nishiyama, M. Nakanishi, H. Leonhardt, T. Konuma, K. Arita

This study determines the structure of the mouse UHRF1 PHD domain complexed with DPPA3, revealing how DPPA3 inhibits UHRF1 chromatin localization through unique interactions.

bioRxiv · Jun 14, 2022Biochemistry