C. Sun

The paper reports that Heimdallarchaeota, a group of archaea, possess proteins associated with photosynthesis and may perform oxygenic photosynthesis, suggesting a photomixotrophic lifestyle.

This study compares SARS-CoV-2 and SARS-CoV spike-RBD binding to ACE2, showing similar affinities but differing neutralizing antibody cross-reactivity, highlighting challenges for broad-spectrum vaccines.

This study analyzes DPANN archaea from deep-sea hydrothermal vents to understand their metabolism and ecological roles, revealing their genomic features and potential contributions to biogeochemical cycles.

This paper introduces SDsSMLM, a spectroscopic single-molecule localization microscopy technique that improves spatial and spectral precision by symmetrically dispersing photons.

This paper establishes an in vitro platform to study CD8+ T cell cytotoxicity against encapsulated cells via indirect antigen recognition, revealing that hydrogel encapsulation blocks direct T cell activation but allows indirect activation through host APCs.

This study determines the cryoEM structure of α-synuclein fibrils with the E46K mutation, revealing a more stable and pathogenic fibril structure compared to wild-type.

This study shows alphaviruses use caveolae-mediated transcytosis across the blood-brain barrier to enter the CNS, and IFN restricts this process.

This study determines cryo-EM structures of alpha-synuclein fibrils with the H50Q mutation, revealing two new polymorphs and structural changes linked to disease mechanisms.

The paper uses single-cell RNA-seq to analyze human Wharton’s Jelly-derived MSCs, identifying heterogeneity in gene expression and potential marker genes for potency.

This study identifies extracellular heparin-binding proteins (HBPs) in normal and acute pancreatitis mouse pancreas and plasma, revealing their roles in homeostasis and inflammation.

This study shows that miR-142-3p binding sites in the 3' UTR of EEEV are critical for virulence, with both canonical and non-canonical sites contributing to virus replication and immune suppression.

The paper identifies major clades of large phage genomes across diverse ecosystems and highlights their expanded genetic repertoires and potential functional roles.

This study compares bacterial composition and functional differences between cancerous and noncancerous ovarian tissues using 16S rRNA sequencing and metagenomic predictions.

This study evaluates how well fecal samples represent chicken gut microbiota, finding that feces can identify most taxa but not fully capture microbial community structure.