Cell-type-specific 3D-genome organization and transcription regulation in the brain
S. Liu, P. Zheng, C. Y. Wang, B. B. Jia, N. R. Zemke, B. Ren, X. Zhuang
The paper investigates 3D-genome organization and transcription regulation in distinct cell types of the mouse brain, finding cell-type-specific nuclear architecture and chromatin compartmentalization correlated with transcriptional activity and MeCP2 regulation.
bioRxiv · Dec 4, 2023Biophysics