S. Sunshine

How Mycobacterium tuberculosis builds a home: Single-cell analysis reveals M. tuberculosis ESX-1-mediated accumulation of anti-inflammatory macrophages in infected mouse lungs.

This study uses single-cell RNA sequencing to show that M. tuberculosis ESX-1 promotes the recruitment and differentiation of anti-inflammatory macrophages in infected mouse lungs.

Global organelle profiling reveals subcellular localization and remodeling at proteome scale

The paper maps subcellular localization of human proteins and shows proteome remodeling during viral infection by combining organelle immuno-capture with mass spectrometry.

Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities

This paper validates a murine proteome-wide PhIP-seq library to identify autoantibody specificities in autoimmune disease models.

Human sialomucin CD164 is an essential entry factor for lymphocytic choriomeningitis virus

This study identifies CD164 as an essential entry factor for LCMV in human cells and tissues, showing its role in viral infection and potential as a therapeutic target.

Persistence of ambigrammatic narnaviruses requires translation of the reverse open reading frame

This paper shows that ambigrammatic narnaviruses require translation of a reverse open reading frame for persistence, suggesting a novel viral strategy involving ribosome-mediated protection of viral RNA.

Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by PhIP-Seq

This study uses PhIP-Seq to identify novel autoantigens in APS1, linking specific autoantibodies to clinical phenotypes like ovarian insufficiency and intestinal dysfunction.