Unique functional responses differentially map onto genetic subtypes of dopamine neurons
Maite Azcorra, Zachary A. Gaertner, Connor Davidson, Qianzi He, Hailey Kim, Shivathmihai Nagappan, Cooper K. Hayes, Charu Ramakrishnan, Lief E. Fenno, Yoon Seok Kim, Karl A. Deisseroth, Richard Longnecker, Rajeshwar B. Awatramani, Daniel A. Dombeck
The paper identifies three genetic dopamine subtypes in the substantia nigra pars compacta, each with distinct functional responses to rewards, aversive stimuli, and movement, showing strong correlation between soma and axon signaling within subtypes.
Nature Neuroscience · Aug 3, 2023Peer-reviewedNeuroscience