Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
J. A. Santos, K. Timinskas, M. H. Lamers, C. Venclovas, D. F. Warner, S. J. Gessner
This study shows that the RecA-NT motif in ImuB is essential for its interaction with ImuA, a RecA homolog, in the mycobacterial mutasome.
bioRxiv · Mar 28, 2023 · PreprintMicrobiology
C. O. Omollo, D. F. Warner, A. Moosa, K. Chibale
This study identifies drug combinations with fusidic acid that show synergistic activity against Mycobacterium tuberculosis in vitro.
bioRxiv · Jan 19, 2023 · PreprintMicrobiology
S. Gessner, Z. A.-M. Martin, M. A. Reiche, J. Santos, N. Dhar, R. Dinkele, T. J. de Wet, A. Ramudzuli, S. Anoosheh, D. M. Lang, J. Aaron, T. L. Chew, J. Herrmann, R. Mueller, J. D. McKinney, , D. F. Warner
This study identifies the molecular composition and function of the mycobacterial mutasome, showing that the ImuB-{beta} clamp interaction is essential for mutagenic DNA repair in mycobacteria.
bioRxiv · Nov 16, 2021Microbiology
M. D. Chengalroyen, M. K. Mason, A. Borsellini, R. Tassoni, G. L. Abrahams, S. Lynch, Y.-M. Ahn, J. Ambler, K. Young, B. M. Crowley, D. B. Olsen, D. F. Warner, C. E. Barry, H. I. M. Boshoff, M. Lamers, V. Mizrahi
This study shows nargenicin binds to Mtb DnaE1 DNA-dependent polymerase, inhibiting replication and inducing DNA damage response in tuberculosis bacteria.
bioRxiv · Oct 27, 2021Microbiology
R. Dinkele, S. Gessner, A. McKerry, B. Leonard, J. Leukes, R. Seldon, D. F. Warner, R. Wood
This study compares Mtb aerosolization during tidal breathing, FVC, and coughing, finding that tidal breathing contributes more Mtb per particle than coughing.
bioRxiv · Oct 17, 2021Microbiology
D. A. Barr, C. O. Omollo, M. Mason, A. Koch, R. J. Wilkinson, D. G. Lalloo, G. Meintjes, V. Mizrahi, D. F. Warner, G. R. Davies
This paper develops a flow cytometry method for absolute counting and single-cell phenotyping of mycobacteria, showing it can detect cell aggregates and reveal subpopulation dynamics not captured by traditional CFU counting.
bioRxiv · May 1, 2021Microbiology
R. Dinkele, S. Gessner, A. S. Koch, C. Morrow, M. Gqada, M. Kamariza, C. Bertozzi, B. Smith, C. McLoud, A. Kamholz, W. Bryden, C. Call, V. Mizrahi, R. Wood, D. F. Warner
This study develops a device to capture and detect live Mycobacterium tuberculosis in bioaerosols, showing high detection rates and suggesting aerosol sources differ from sputum.
PLOS Pathogens · Feb 1, 2021Peer-reviewedMicrobiology
T. Kipkorir, G. T. Mashabela, T. J. de Wet, A. S. Koch, L. Wiesner, V. Mizrahi, D. F. Warner
This study investigates cobalamin biosynthesis, transport, and its role in methionine biosynthesis in M. smegmatis, revealing cobalamin-dependent regulation of methionine synthase expression.
bioRxiv · Nov 4, 2020Microbiology
T. J. de Wet, K. R. Winkler, M. M. Mhlanga, V. Mizrahi, D. F. Warner
The paper uses CRISPRi and imaging to analyze morphological changes in M. smegmatis, revealing gene function clusters and a new restriction-modification system.
bioRxiv · Mar 20, 2020Microbiology