Author

Y.-M. Ahn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Assay:imaging· 1 Organism:non-human primate· 1

Frequent Co-Authors

C. E. Barry· 2 shared A. Borsellini· 1 shared A. E. Jerse· 1 shared A. G. White· 1 shared B. G. Davis· 1 shared B. Kreiswith· 1 shared B. M. Crowley· 1 shared C. A. Scanga· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

C. E. Barry

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Distributable, Metabolic PET Reporting of Tuberculosis

R. M. N. Khan, Y.-M. Ahn, G. A. Marriner, L. E. Via, F. D'Hooge, S. S. Lee, N. Yang, F. Basuli, A. G. White, J. A. Tomko, L. J. Frye, C. A. Scanga, D. M. Weiner, M. L. Sutphen, D. M. Schimel, , B. G. Davis

This paper introduces [18F]FDT, a PET tracer that specifically images Mycobacterium tuberculosis lesions and monitors treatment, enabling global access through a simple synthesis method from [18F]FDG.

bioRxiv · Apr 3, 2023Biochemistry

A novel oral GyrB/ParE dual binding inhibitor effective against multidrug resistant Neisseria gonorrhoeae and other high-threat pathogens

S. Park, R. Russo, L. Westfall, R. Shrestha, M. Zimmerman, V. A. Dartois, N. Kurepina, B. Kreiswith, E. Singleton, S.-G. LI, N. Mittal, Y.-M. Ahn, j. Bilotta, K. L. Connolly, A. E. Jerse, , D. S. Perlin

The paper describes a novel oral inhibitor, JSF-2659, effective against multidrug-resistant Neisseria gonorrhoeae and other high-threat pathogens, with low potential for resistance development.

bioRxiv · Mar 23, 2022Microbiology

DNA-dependent binding of nargenicin to DnaE1 inhibits replication in Mycobacterium tuberculosis

M. D. Chengalroyen, M. K. Mason, A. Borsellini, R. Tassoni, G. L. Abrahams, S. Lynch, Y.-M. Ahn, J. Ambler, K. Young, B. M. Crowley, D. B. Olsen, D. F. Warner, C. E. Barry, H. I. M. Boshoff, M. Lamers, V. Mizrahi

This study shows nargenicin binds to Mtb DnaE1 DNA-dependent polymerase, inhibiting replication and inducing DNA damage response in tuberculosis bacteria.

bioRxiv · Oct 27, 2021Microbiology