Author

D. J. Sanderson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

A. F. Schubert· 1 shared A. R. Fehr· 1 shared C. Brenner· 1 shared C. D. Heer· 1 shared C. G. Roberts· 1 shared D. Komander· 1 shared H. Ovaa· 1 shared J. N. Pruneda· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. F. Schubert

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2 papers

Recent·Most cited

Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

C. D. Heer, D. J. Sanderson, L. S. Voth, Y. M. O. Alhammad, M. S. Schmidt, S. A. J. Trammell, S. Perlman, M. S. Cohen, A. R. Fehr, C. Brenner

This study shows that SARS-CoV-2 infection upregulates MARylating PARPs and NAD synthesis enzymes, and that enhancing NAD levels can reduce viral replication.

bioRxiv · Apr 17, 2020Microbiology

Identification and characterization of diverse OTU deubiquitinases in bacteria

A. F. Schubert, J. V. Nguyen, T. G. Franklin, P. P. Geurink, C. G. Roberts, D. J. Sanderson, L. N. Miller, H. Ovaa, K. Hofmann, J. N. Pruneda, D. Komander

The paper identifies and characterizes OTU deubiquitinases in bacteria, showing their structural and functional similarities to human and viral OTUs.

bioRxiv · Mar 28, 2020Biochemistry