Optimizing multifunctional fluorescent ligands for intracellular labeling
P. Kumar, J. D. Vevea, A. N. Tkachuk, K. Campbell, E. T. Watson, A. X. Ayala, J. B. Grimm, E. R. Chapman, D. J. Solecki, L. D. Lavis
The paper designs cell-permeable multifunctional ligands for HaloTag fusions that enable protein labeling and translocation, using Si-rhodamines with low KL-Z and high logD7.4 values.
bioRxiv · Jul 2, 2022 · PreprintCell Biology