Author

D. Jourd'heuil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Jaitovich· 2 shared C. Mathai· 2 shared F. Jourd'heuil· 2 shared J. Balnis· 2 shared J. Barra· 2 shared K. Gilliard· 2 shared L. G. C. Pham· 2 shared M. Barroso· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

A. Jaitovich

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nuclear cytoglobin associates with HMGB2 and regulates DNA damage and genome-wide transcriptional output in the vasculature

C. Mathai, F. Jourd'heuil, L. G. C. Pham, K. Gilliard, D. Howard, J. Balnis, A. Jaitovich, S. Chittur, M. Riley, R. Peredo-Wende, A. Ibrahim, S. Shin, M. Barroso, J. Barra, E. Shishkova, , D. Jourd'heuil

This study identifies nuclear cytoglobin's role in regulating DNA damage and transcriptional output in vascular smooth muscle cells through its interaction with HMGB2.

bioRxiv · May 10, 2023Cell Biology

A role for cytoglobin in regulating intracellular hydrogen peroxide and redox signals in the vasculature

C. Mathai, F. L. Jourd'heuil, L. G. C. Pham, K. Gilliard, J. Balnis, A. Jen, K. A. Overmyer, J. J. Coon, A. Jaitovich, B. Boivin, D. Jourd'heuil

This study shows cytoglobin regulates intracellular hydrogen peroxide and redox signals by reducing hyperoxidation of peroxiredoxins and facilitating Hyper7 reduction, independent of heme-based hydrogen peroxide reactions.

bioRxiv · Mar 31, 2023 · PreprintBiochemistry

DMT1 bridges endosomes and mitochondria to modulate mitochondrial iron translocation

J. Barra, I. Crosbourne, L. Wang, R. Bossardi-Ramos, F. Jourd'heuil, I. Nelson, A. P. Adam, D. T. Corr, D. Jourd'heuil, M. Barroso

This study shows DMT1 modulates mitochondrial iron translocation in invasive breast cancer cells by bridging endosomes and mitochondria, affecting iron levels and mitochondrial function.

bioRxiv · Apr 14, 2022Cell Biology

Sub-lethal radiation-induced senescence impairs resolution programs and drives cardiovascular inflammation

S. Sadhu, C. Decker, B. E. Sansbury, M. Marinello, A. Seyfried, J. Howard, M. Mori, Z. Hosseini, T. Arunachalam, A. V. Finn, J. M. Lamar, D. Jourd'heuil, L. Guo, K. C. MacNamara, M. Spite, G. Fredman

This study shows sub-lethal radiation induces macrophage senescence, impairing efferocytosis and promoting cardiovascular inflammation, with RvD1 treatment reversing these effects.

bioRxiv · May 19, 2021Immunology