Author

E. Shishkova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2

Frequent Co-Authors

J. J. Coon· 4 shared A. D. Attie· 2 shared A. Jen· 2 shared D. J. Pagliarini· 2 shared J. Coon· 2 shared K. A. Overmyer· 2 shared K. L. Schueler· 2 shared L. K. Muehlbauer· 2 shared

Activity by Year

2023-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersBiochemistry

J. J. Coon

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Substrate-directed control of N-glycosylation in the endoplasmic reticulum calibrates signal reception at the cell-surface

R. Rohatgi, M. Ma, R. Dubey, A. Jen, G. V. Pusapati, E. Shishkova, K. A. Overmyer, V. Cormier-Daire, L. Aravind, J. J. Coon

The paper identifies an ER pathway that regulates N-glycosylation by modulating OST-A activity, impacting cell-surface signaling and tissue development.

bioRxiv · Apr 25, 2024 · PreprintCell Biology

Heme biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue

D. J. Duerre, J. K. Hansen, S. John, A. Jen, N. Carrillo, H. Bui, Y. Bao, M. Fabregat, K. Overmyer, E. Shishkova, M. P. Keller, R. A. Anderson, V. L. Cryns, A. D. Attie, J. Coon, , A. Galmozzi

This study shows that heme biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue by affecting UCP1 and mitochondrial function.

bioRxiv · Nov 28, 2023 · PreprintCell Biology

Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15

J. Davidson, R. Jain, T. Kizzar, G. Geoghegan, D. J. Nesbitt, A. T. Cavanagh, A. Abe, A. Hunger, X. Chao, I. James, D. Baldwin, R. Verma, K. L. Schueler, V. Hinkoka-Galcheva, S. Michorowska, , J. Simcox

The paper identifies TFEB regulation of BMP lipid catabolism via Pla2g15, showing increased BMP lipids in Pla2g15 knockout mice and cold intolerance upon TFEB knockdown.

bioRxiv · Nov 3, 2023Biochemistry

Nuclear cytoglobin associates with HMGB2 and regulates DNA damage and genome-wide transcriptional output in the vasculature

C. Mathai, F. Jourd'heuil, L. G. C. Pham, K. Gilliard, D. Howard, J. Balnis, A. Jaitovich, S. Chittur, M. Riley, R. Peredo-Wende, A. Ibrahim, S. Shin, M. Barroso, J. Barra, E. Shishkova, , D. Jourd'heuil

This study identifies nuclear cytoglobin's role in regulating DNA damage and transcriptional output in vascular smooth muscle cells through its interaction with HMGB2.

bioRxiv · May 10, 2023Cell Biology

Hem25p is a mitochondrial IPP transporter

J. Tai, R. M. Guerra, S. W. Rogers, Z. Fang, L. K. Muehlbauer, E. Shishkova, K. A. Overmyer, J. J. Coon, D. J. Pagliarini

The paper identifies Hem25p as a mitochondrial IPP transporter in yeast, essential for CoQ biosynthesis.

bioRxiv · Mar 14, 2023 · PreprintBiochemistry

Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

N. M. Niemi, L. R. Serrano, L. K. Muehlbauer, C. Balnis, K.-L. Kozul, E. H. Rashan, E. Shishkova, K. L. Schueler, M. P. Keller, A. D. Attie, J. Pagan, J. J. Coon, D. J. Pagliarini

This study shows that Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy, leading to metabolic defects and early lethality in mice.

bioRxiv · Feb 28, 2023Biochemistry