Author

J. Kralova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Agrawal· 1 shared A. Drobek· 1 shared A. Mayo· 1 shared A. Raanan· 1 shared A. Solomon· 1 shared B. Dolensky· 1 shared D. Aizik· 1 shared D. Glatzova· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. Agrawal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Murine GMP- and MDP-derived classical monocytes have distinct functions and fates

S. Trzebanski, J.-S. Kim, N. Larrossi, D. Kancheva, J. Bastos, M. Haddad, D. Aizik, J. Kralova, M. Gross-Vered, S. Boura-Halfon, T. Lapidot, R. Alon, K. Movahedi, S. Jung, E. Sivan, , A. Raanan

This study identifies distinct functions and fates of murine classical monocytes derived from GMP and MDP, showing differential contributions to tissue macrophage populations.

bioRxiv · Jul 29, 2023Immunology

p16-dependent upregulation of PD-L1 impairs immunosurveillance of senescent cells

J. Majewska, A. Agrawal, A. Mayo, L. Roitman, R. Chatterjee, J. Kralova, T. Landsberger, Y. Katzenelenbogen, T. M. Salame, E. Hagai, N. Stanojevic, I. Amit, U. Alon, V. Krizhanovsky

This study identifies p16-dependent upregulation of PD-L1 in senescent cells as a mechanism to evade immune clearance, showing that anti-PD-L1 treatment can eliminate these cells.

bioRxiv · Jan 30, 2023 · PreprintCell Biology

Regulation of neutrophil NADPH oxidase by PSTPIP2 affects bone damage in murine autoinflammatory osteomyelitis

J. Kralova, A. Drobek, J. Prochazka, F. Spoutil, D. Glatzova, S. Borna, J. Pokorna, T. Skopcova, P. Angelisova, M. Gregor, P. Kovarik, R. Sedlacek, T. Brdicka

This study shows that PSTPIP2 regulates neutrophil NADPH oxidase, and its loss leads to increased ROS production and bone damage in a murine model of autoinflammatory osteomyelitis.

bioRxiv · Aug 6, 2019 · PreprintImmunology

Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders

J. Kralova, M. Jurasek, L. Krcova, B. Dolensky, I. Novotny, M. Dusek, Z. Rottnerova, M. Kahle, P. Drasar, P. Bartunek, V. Kral

This paper develops fluorescent probes for live monitoring of cholesterol trafficking and demonstrates their utility in identifying lysosomal storage disorders.

bioRxiv · Feb 19, 2018Cell Biology