Author

D. Rajendran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Organism:zebrafish· 2

Frequent Co-Authors

G. Danuser· 5 shared T. Isogai· 3 shared B.-J. Chang· 2 shared F. Zhou· 2 shared H. Mazloom-Farsibaf· 2 shared K. M. Dean· 2 shared R. P. Fiolka· 2 shared V. S. Murali· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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5 shared papersCell Biology

G. Danuser

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Author profile →

8 papers

Recent·Most cited

Anchorage-independent cell proliferation promoted by fascin's F-actin bundling

T. Isogai, V. S. Murali, F. Zhou, X. Wang, D. Rajendran, L. P. Castro, N. Venkateswaran, M. Conacci-Sorrell, G. Danuser

This study identifies fascin-1's role in promoting anchorage-independent proliferation through a novel signaling complex called PASS, which drives Rac1/PAK/JNK signaling in cancer cells.

bioRxiv · May 4, 2024 · PreprintCell Biology

Adaptive Optics in an Oblique Plane Microscope

C. McFadden, Z. Marin, B. Chen, S. Daetwyler, X. Wang, D. Rajendran, R. P. Fiolka

This paper demonstrates adaptive optics in an oblique plane microscope, improving resolution and signal strength in zebrafish embryos.

bioRxiv · Mar 21, 2024Cell Biology

RhoA activation promotes glucose uptake to elevate proliferation in MAPK inhibitor resistant melanoma cells.

V. Siruvallur Murali, D. Rajendran, T. Isogai, R. J. DeBerardinis, G. Danuser

This study identifies RhoA activation as a driver of glucose uptake and proliferation in MAPK inhibitor-resistant melanoma cells through ROCK-mediated IRS1 and PI3K pathway activation.

bioRxiv · Jan 9, 2024 · PreprintCancer Biology

Keratin isoform shifts modulate motility signals during wound healing

B. A. Nanes, K. Bhatt, R. Boujemaa-Paterski, E. Azarova, S. Munawar, D. Rajendran, T. Isogai, K. M. Dean, O. Medalia, G. Danuser

The paper shows that keratin isoform shifts during wound healing modulate motility signals by activating myosin motors through isoform-specific interactions with vimentin shuttling kinases.

bioRxiv · May 4, 2023Cell Biology

In vivo profiling of site-specific human cancer cell states in zebrafish

D. Segal, H. Mazloom-Farsibaf, B.-J. Chang, P. Roudot, D. Rajendran, M. Warren, R. Fiolka, J. Amatruda, G. Danuser

The paper uses zebrafish xenografts and computer vision to study how Ewing Sarcoma cell morphology changes in different sites and under EWSR1-FLI1 expression variations.

bioRxiv · Jun 9, 2021Cancer Biology

Blebs Promote Cell Survival by Assembling Oncogenic Signaling Hubs

A. D. Weems, E. S. Welf, M. K. Driscoll, F. Zhou, H. Mazloom-Farsibaf, B.-J. Chang, V. S. Murali, G. M. Gihana, B. G. Weiss, J. Chi, D. Rajendran, K. M. Dean, R. P. Fiolka, G. Danuser

This study shows blebs form signaling hubs that promote anoikis resistance in cancer cells by recruiting septins and activating ERK/PI3K pathways.

bioRxiv · Apr 23, 2021Cell Biology

TAZ-CAMTA1 and YAP-TFE3 modulate the basal TAZ/YAP transcriptional program by recruiting the ATAC histone acetyltransferase complex

N. Merritt, K. Garcia, D. Rajendran, Z.-Y. Lin, X. Zhang, K. Mitchell, N. Borcherding, C. Fullenkamp, M. Chimenti, A.-C. Gingras, K. Harvey, M. R. Tanas

This study identifies the ATAC histone acetyltransferase complex as an oncogenic driver in EHE by showing TAZ-CAMTA1 and YAP-TFE3 recruit it to modulate transcription and chromatin structure.

bioRxiv · Sep 7, 2020Cancer Biology

Chemical composition and larvicidal activity against Aedes mosquitoes of flower extracts from Clitoria Ternatea

R. Ravi, M. F. Mohd Amin, A. R. Said, I. H. Ishak, S. Srikumar, D. Rajendran, M. S. Mat Rasat, P. Ramaiah, M. Bharathithasan, D. R. Ravindran, As stated in manuscript

This study identifies chemical compounds from Clitoria ternatea flower extracts and evaluates their larvicidal activity against Aedes mosquito larvae, showing effectiveness with LC50 values and no toxicity to fish.

bioRxiv · Mar 31, 2020Biochemistry